SoleChem

1,3-dimethylurea

CAS
96-31-1
EC
202-498-7
Mol. Weight
88.11 g/mol

Description

1,3-Dimethylurea (CAS 96-31-1), commonly abbreviated as DMU, is a symmetric disubstituted urea derivative used as a chemical intermediate and reagent across pharmaceutical and specialty chemical manufacturing.

It functions primarily as a building block in synthesis pathways and as a component in buffering and catalytic systems. In pharmaceutical manufacturing, DMU serves as an intermediate in the synthesis of active pharmaceutical ingredients.

This includes methylxanthine derivatives and heterocyclic compounds requiring a dimethylurea scaffold. Personal care formulators incorporate it into preservation systems where controlled release of antimicrobial activity is required.

In biotechnology research and process chemistry, DMU is used to stabilize pH in buffered reaction media. This supports enzyme activity and cell culture conditions during various stages of chemical development.

Catalyst precursor applications include its use in the preparation of nitrogen-containing ligands and coordination complexes for specialty chemical synthesis. It is a versatile reagent for modern industrial chemistry.

1,3-Dimethylurea is supplied as a white crystalline powder or granular solid. It is available in technical grade for industrial synthesis and in higher-purity grades suitable for pharmaceutical intermediate use.

Specifications are aligned to USP and Ph. Eur. reference standards where required. Packaging typically ranges from kilogram-scale laboratory quantities to bulk industrial supply for large operations.

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Physical Properties

Melting Point 108 °C
Boiling Point 268-270 °C
Density 1.142 g/cm³
Flash Point 157 °C
Appearance white crystals
Color White
Form Crystals
Water Solubility 765 g/L (21.5 ºC)
Vapor Pressure 6 hPa (115 °C)
Refractive Index 1.4715 (estimate)
pH 9.0-9.5 (100g/l, H2O, 20℃)
Log P -0.783 at 25℃

Safety & Handling (Learn More)

Warning GHS08
Hazard Statements
H373 May causes damage to organs through prolonged or repeated exposure
Precautionary Statements
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P319 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container in accordance with local regulations.

Trade & Regulatory

HS Code 29241900
Storage Class 11 - Combustible Solids
WGK (Germany) 1

Documentation

Other Names

N,N'-Dimethylurea|sym-Dimethylurea|Urea, N,N'-dimethyl-|Symmetric dimethylurea|Urea, 1,3-dimethyl-|N,N'-Dimethylharnstoff|WAM6DR9I4X|DMU

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