N,N-Dimethylacetoacetamide

N,N-Dimethylacetoacetamide (CAS 2044-64-6), commonly abbreviated as DMAA, is a beta-ketoamide building block used in pharmaceutical synthesis, agrochemical development, and polymer chemistry.

Where is N,N-Dimethylacetoacetamide used?

• Pharmaceutical manufacturing: key intermediate in the synthesis of active pharmaceutical ingredients, particularly where a beta-ketoamide motif is required for cyclization reactions
• Agrochemical production: preparation of herbicide and pesticide intermediates, where its reactivity toward nitrogen and carbon nucleophiles enables efficient route design
• Polymer chemistry: functional monomer or co-monomer to introduce reactive ketone groups into polymer backbones, influencing crosslinking behavior and adhesion properties
• Specialty resin formulators incorporate it where controlled reactivity during polymerization is a process requirement.

Commercial specifications

• Material is typically 97% or higher for synthesis-grade material.
• It is generally packaged in drums or intermediate bulk containers suited to industrial volumes.