Lipoprotein lipase

Lipoprotein lipase (CAS 9004-02-8), also known as clearing factor lipase, is an enzyme that catalyzes the hydrolysis of triglycerides in lipoproteins, releasing free fatty acids for cellular uptake.

In industrial and research contexts, it functions as a biocatalytic tool for lipid processing, diagnostic assay development, and metabolic pathway research. In pharmaceutical research, it is used to model lipid metabolism disorders.

This enzyme supports drug discovery programs targeting dyslipidemia and cardiovascular conditions. Diagnostic kit manufacturers incorporate it into enzymatic assay systems for measuring triglyceride levels in clinical laboratory testing.

Biotechnology applications include its use as a reagent in lipoprotein characterization studies and in vitro metabolic modeling. It also supports formulation research where controlled lipid hydrolysis is required.

This is essential to evaluate lipid-based drug delivery systems. The product is supplied as a lyophilized powder or liquid enzyme preparation, typically in buffered solution formats suited for laboratory and research-scale use.

Activity is expressed in units per milligram of protein, with specifications varying by source organism, commonly bovine or bacterial origin. Research-grade and reagent-grade designations are standard for these materials.

Buyers should confirm specific activity, purity, and storage requirements when sourcing. The material is handled according to strict laboratory protocols to ensure the stability and efficacy of the enzymatic activity.