Pancreatin
What is Pancreatin?
Pancreatin (CAS 8049-47-6) is a multi-enzyme concentrate derived from porcine or bovine pancreatic tissue, containing a defined mixture of proteases, lipases, and amylases.
Where is Pancreatin used?
- Pharmaceuticals: active substance in pancreatic enzyme replacement therapy products, often enteric-coated capsules or tablets for exocrine pancreatic insufficiency
- Food and nutrition: production of protein hydrolysates and pre-digested formulas, including hypoallergenic infant feed ingredients
- Biotechnology and research: in vitro digestion models, bioavailability testing, and preparation of peptide fractions
- Leather and textile industries: bating and degumming processes requiring controlled proteolytic activity
- It is essential where enzymatic digestion or hydrolysis of proteins, fats, and starches is required.
Good to know: Cold-chain handling is typically required during transport and storage to preserve enzymatic activity.
Commercial specifications
- Standard grades include USP, BP, and Ph. Eur.
- Potency specifications such as 4X, 8X, and 10X relative to the reference standard
- Bulk supply in fiber drums or multi-layer bags
Other Names (Synonyms)
2-(benzylsulfonyl)-1-(morpholin-4-yl)ethanone|Pancreatin, from porcine stomach mucose|Diastase vera|Intrazyme|Pankreon|Pancrex V