Pancreatin

Pancreatin (CAS 8049-47-6) is a multi-enzyme concentrate derived from porcine or bovine pancreatic tissue, containing a defined mixture of proteases, lipases, and amylases. It is used across pharmaceutical, food processing, and biotechnology applications. This substance is essential where enzymatic digestion or hydrolysis of proteins, fats, and starches is required. In pharmaceutical manufacturing, it is the active substance in pancreatic enzyme replacement therapy products.

These products are often formulated as enteric-coated capsules or tablets for patients with exocrine pancreatic insufficiency. Food and nutrition manufacturers use it to produce protein hydrolysates and pre-digested formulas. It is also a key component in hypoallergenic infant feed ingredients. Biotechnology and research applications rely on this enzyme for in vitro digestion models, bioavailability testing, and the preparation of peptide fractions.

The material is also used in the leather and textile industries for bating and degumming processes where controlled proteolytic activity is needed. It is supplied as an off-white to tan powder with activity expressed in units. Standard grades include USP, BP, and Ph. Eur., with potency specifications such as 4X, 8X, and 10X relative to the reference standard. Each enzyme component is measured for specific activity levels.

Bulk supply is available in fiber drums or multi-layer bags to ensure product integrity. Cold-chain handling is typically required during transport and storage to preserve the enzymatic activity of the material.