8(S)-HETE
What is 8(S)-HETE?
8(S)-HETE (CAS 105500-09-2) is a hydroxyeicosatetraenoic acid produced endogenously; also referenced in research contexts as 8(R)-HETE when specifying stereoisomeric counterparts.
Where is 8(S)-HETE used?
- Pharmaceutical research: analytical reference standard for quantifying hydroxy-fatty acid profiles in biological samples
- Biotechnology laboratories: receptor binding assays and enzyme activity studies focused on lipoxygenase and cytochrome P450 pathways
- Metabolomics and lipidomics platforms: certified reference material for method validation and calibration
- It serves as a reference standard and research reagent in eicosanoid biology.
Good to know: Precise stereochemical identity is critical for reproducible results in these studies. The product is unstable in neat form.
Commercial specifications
- Solution, typically in ethanol or a compatible organic solvent
- Standard pack sizes range from microgram to low-milligram quantities
- Research-grade purity with a certificate of analysis confirming stereochemical identity and concentration
Other Names (Synonyms)
Eicosatetraenoic acid|(5Z,8R,9E,11Z,14Z)-8-hydroxyicosa-5,9,11,14-tetraenoic acid|8(r)-hete