8(S)-HETE

CAS Number
105500-09-2

What is 8(S)-HETE?

8(S)-HETE (CAS 105500-09-2) is a hydroxyeicosatetraenoic acid produced endogenously; also referenced in research contexts as 8(R)-HETE when specifying stereoisomeric counterparts.

Where is 8(S)-HETE used?

  • Pharmaceutical research: analytical reference standard for quantifying hydroxy-fatty acid profiles in biological samples
  • Biotechnology laboratories: receptor binding assays and enzyme activity studies focused on lipoxygenase and cytochrome P450 pathways
  • Metabolomics and lipidomics platforms: certified reference material for method validation and calibration
  • It serves as a reference standard and research reagent in eicosanoid biology.

Good to know: Precise stereochemical identity is critical for reproducible results in these studies. The product is unstable in neat form.

Commercial specifications

  • Solution, typically in ethanol or a compatible organic solvent
  • Standard pack sizes range from microgram to low-milligram quantities
  • Research-grade purity with a certificate of analysis confirming stereochemical identity and concentration

Other Names (Synonyms)

Eicosatetraenoic acid|(5Z,8R,9E,11Z,14Z)-8-hydroxyicosa-5,9,11,14-tetraenoic acid|8(r)-hete

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What are the physical properties of 8(S)-HETE?

Boiling Point 471.1±45.0 °C(Predicted)
Density 0.984±0.06 g/cm3(Predicted)

Which trade and regulatory codes apply to 8(S)-HETE?

UN Number 1170
ADR Class 3
Packing Group II
WGK (Germany) 3
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