Enramycin
Description
Enramycin (CAS 11115-82-5), also known as Enduracidin, is a polypeptide antibiotic produced by fermentation of Streptomyces fungicidicus. In commercial use, it functions as an antimicrobial growth promoter and feed preservative.
The compound works by inhibiting gram-positive bacterial cell wall synthesis in livestock. In animal nutrition, it is incorporated into medicated premixes and compound feeds for broilers, swine, and cattle.
This additive helps to improve feed conversion ratios and suppress pathogenic gut flora. It is used in veterinary pharmaceutical formulations where targeted activity against Clostridium species is required.
In biotechnology and life sciences research, Enduracidin serves as a reference compound for studying bacterial cell wall biosynthesis inhibition. Its structural complexity positions it as a pharmaceutical intermediate.
Enramycin is supplied as a powder, typically standardized to 8% or 4% active content in premix carrier form for feed applications. Pure technical and research-grade material is available for laboratory use.
Specifications are generally aligned with veterinary pharmacopoeia standards or manufacturer-defined assay requirements. Quality control ensures the product meets necessary safety and efficacy benchmarks for global trade.
Physical Properties
| Melting Point | 238-245 °C (decomp) |
| Color | Light brown to brown |
| Form | Solid |
Trade & Regulatory
| WGK (Germany) | 2 |
Documentation
Other Names
Enduracidin|4-[[41-(4-aminobutyl)-9,23-bis[(2-amino-4,5-dihydro-1H-imidazol-4-yl)methyl]-26-[3-(carbamoylamino)propyl]-14-(3,5-dichloro-4-hydroxyphenyl)-29,38-bis(1-hydroxyethyl)-17-(hydroxymethyl)-3,20,32,35,43-pentakis(4-hydroxyphenyl)-6,47-dimethyl-2,5,8,11,13,16,19,22,25,28,31,34,37,40,42,45-hexadecaoxo-1-oxa-4,7,10,12,15,18,21,24,27,30,33,36,39,41,44-pentadecazacycloheptatetracont-46-yl]amino]-3-[[(2E,4E)-10-methyldodeca-2,4-dienoyl]amino]-4-oxobutanoic acid;hydrate
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