Benzethonium chloride

CAS Number
121-54-0
EC Number
204-479-9
Abbreviation
BZT

What is Benzethonium chloride?

Benzethonium chloride (CAS 121-54-0), commonly abbreviated as BZT, is a quaternary ammonium compound used as a broad-spectrum antimicrobial and preservative.

Where is Benzethonium chloride used?

  • Pharmaceutical formulations: preservative in topical antiseptics, ophthalmic preparations and wound care products
  • Personal care: hand sanitizers, skin cleansers and cosmetic preservative systems, as primary or co-preservative
  • Industrial and institutional cleaning: active biocidal agent in surface disinfectants and sanitizing concentrates for healthcare and food-processing environments
  • Water treatment and industrial processes: biocide controlling microbial growth in recirculating systems and cooling towers
  • It disrupts microbial cell membranes, making it effective against bacteria, fungi, and some viruses at low use concentrations.

Good to know: USP is the most commonly specified grade for pharmaceutical and personal care procurement.

Commercial specifications

  • Bulk quantities in fiber drums or multi-layer bags
  • Powder in drums; liquid grades in IBC or drum packaging

Other Names (Synonyms)

p-tert-octylphenoxyethoxyethyldimethylbenzylammonium chloride|p-diisobutyl phenoxyethoxyethyl dimethyl benzylammonium chloride|diisobutylphenoxyethoxyethyldimethyl benzyl ammonium chloride|BZT|benzyldimethyl-p-(1,1,3,3-tetramethylbutyl)phenoxyethoxy-ethylammonium chloride|benzetonium chloride|{2-[2-(4-diisobutylphenoxy)ethoxy]ethyl}dimethylbenzylammonium chloride|Hyamine

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What are the physical properties of Benzethonium chloride?

Melting Point 164-166 °C
Boiling Point 162°C[at 101 325 Pa]
Density 0.998 g/mL at 20 °C
Appearance White Powder
Color White
Odor Odorless
Form Liquid
Water Solubility 1-5 g/100 mL at 18 ºC
Vapor Pressure < 0.001 hPa @ 2°C
Refractive Index 1.5650 (estimate)
pH 5.5-7.5 (25℃, 0.1M in H2O)
Log P 1.08 at 20℃

How is Benzethonium chloride classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS06· Toxic GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H301 H301
H302 H302
H314 H314
H315 H315

Precautionary Statements

P260 P260
P264 P264
P270 P270
P273 P273

Which trade and regulatory codes apply to Benzethonium chloride?

HS Code 29239000
UN Number 1759
Storage Class 6.1A - Combustible, acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany) 2
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