Vitamin B5 Pantethine

Vitamin B5 Pantethine (CAS 16816-67-4) is the disulfide form of pantetheine, the active coenzyme precursor derived from pantothenic acid within the Vitamin B5 family.

Where is Vitamin B5 Pantethine used?

• Nutraceuticals and dietary supplements: listed as pantethine in Annex II of Directive 2002/46/EC, an approved vitamin source for EU food supplement formulations; authorised EU health claims under Regulation (EC) No 432/2012 recognise that Vitamin B5 contributes to normal energy-yielding metabolism, mental performance, synthesis of steroid hormones and vitamin D, and reduction of tiredness and fatigue
• Pharmaceutical and healthcare manufacturing: material supplied to standards aligned with recognised pharmacopoeial requirements
• Personal care and cosmetics: humectant and moisturising active supporting skin barrier hydration and conditioning
• Leave-on formulations, hair care products and topical preparations: softening and plasticising properties for moisture retention and substrate flexibility
• It may also contribute to cross-linking interactions relevant to film-forming cosmetic systems.

Good to know: Distinct from calcium pantothenate, pantethine carries higher biological activity at the cellular level. Buyers specifying material for finished-dose applications should confirm applicable grade requirements and may request certificates of analysis, HPLC purity data and full regulatory dossiers.

Commercial specifications

• Food-grade and pharma-grade material available
• Hygroscopic solid; store cool, dry, away from moisture and direct light
• Standard packaging: 25 kg drums or fibre cartons; smaller pack sizes for development batches