2,3,4-Trihydroxybenzaldehyde
Description
2,3,4-Trihydroxybenzaldehyde (CAS 2144-08-3), also referenced as 2,3,4-THB, is a polyphenolic aldehyde used across pharmaceutical, cosmetic, and specialty chemical applications.
It functions as an antioxidant, antimicrobial agent, and UV stabilizer in formulated products. In pharmaceutical development, 2,3,4-THB serves as a bioactive intermediate and antioxidant stabilizer.
It is utilized in active ingredient synthesis and finished dosage formulations. Cosmetic formulators incorporate it into skincare products for its UV-protective and preservation properties.
This is particularly useful in formulations targeting oxidative stress or requiring extended shelf stability. Its aldehyde and phenolic character make it relevant in flavor and fragrance compounding.
It contributes to aromatic profiles in specialty applications. Research and fine chemical manufacturers also source it as a building block for synthesizing heterocyclic compounds and novel bioactive molecules.
2,3,4-Trihydroxybenzaldehyde is supplied as a solid crystalline powder. It is available primarily in research and technical grades, with high-purity specifications typically exceeding 98%.
These grades are suited to pharmaceutical intermediates and specialty formulation work. Packaging ranges from small laboratory quantities to bulk orders depending on specific supplier capability.
Physical Properties
| Melting Point | 230 °C (decomp) |
| Boiling Point | 237.46°C (rough estimate) |
| Density | 1.3725 (rough estimate) |
| Appearance | light brown to beige-brown powder |
| Color | Light brown to beige-brown |
| Form | Powder |
| Water Solubility | 1.541g/L at 25℃ |
| Refractive Index | 1.6400 (estimate) |
| Log P | 1.25 |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29124990 |
| WGK (Germany) | 2 |
Documentation
Other Names
Benzaldehyde, 2,3,4-trihydroxy-|3-08-00-03357 (Beilstein Handbook Reference)|3,4-Dihydroxysalicylaldehyde|2,3,4-Trihydroxybenzaldeyde|SOY OLIGOSACCHARIDE|2,3,4-THB
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