SoleChem

4-hydroxy acetophenone

Heterocyclic Compounds Food & Nutrition
CAS
99-93-4
EC
202-802-8
Mol. Weight
136.15 g/mol

Description

4-Hydroxyacetophenone (CAS 99-93-4), also known commercially as piceol, is a phenolic ketone used across food, cosmetic, and industrial manufacturing. It functions as a photoinitiator, antioxidant, and flavoring agent depending on the application sector.

In UV-curable systems for printing inks and packaging coatings, it acts as a photoinitiator to trigger polymerization under UV exposure. Cosmetic formulators incorporate it as an antioxidant and skin-brightening active in serums and creams.

In food and beverage, it is approved under FEMA 4330 as a flavoring ingredient, contributing subtle phenolic and sweet notes to finished products. It is also used as an intermediate in the synthesis of active pharmaceutical ingredients.

Pharmaceutical manufacturers source it particularly where a para-substituted acetophenone scaffold is required. The material is supplied as a white to off-white crystalline powder available in various technical and high-purity grades.

Our product meets rigorous quality standards including FCC, USP, Ph.Eur., BP, EP, and ACS specifications. These grades are suited to pharmaceutical and food-grade requirements for global distribution.

Standard packaging options include fiber drums and multi-layer bags, with bulk quantities available for industrial procurement. We ensure consistent quality and reliable supply chains for all manufacturing sectors.

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Physical Properties

Melting Point 109.5 °C
Boiling Point 146-149 °C
Density 1.278 g/cm³ @ Temp: 25 °C
Flash Point 166 °C
Appearance almost white to beige crystalline powder
Color Almost white to beige
Odor at 10.00 % in dipropylene glycol. mild sweet hawthorn balsam mimosa
Form Crystalline Powder
Water Solubility 10 g/L (22 ºC)
Vapor Pressure 0.002Pa at 20℃
Refractive Index 1.5577 (estimate)
Log P 1.35 at 25℃

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H412 Harmful to aquatic life with long lasting effects
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29145000
Storage Class 13 - Non Combustible Solids
WGK (Germany) 3

Documentation

Other Names

piceol|para-Hydroxyacetophenone|p-Hydroxyphenyl methyl ketone|p-Hydroxyacetophenone|Methyl p-hydroxyphenyl ketone|4-Acetylphenol|1-(4-hydroxyphenyl)ethanone|(4-hydroxyphenyl)ethan-1-one

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