Polydioxanone

Polydioxanone (CAS 31621-87-1), also referenced commercially as Resomer X 210 and Resomer X 206S, is a biodegradable, absorbable polyester polymer used across medical device manufacturing and pharmaceutical applications.

It degrades predictably in biological environments through hydrolysis, making it a controlled-release and structural material of choice where temporary implantation is required for patients.

Polydioxanone is the base material for absorbable monofilament sutures, where its flexibility and sustained tensile strength retention over several weeks meet the mechanical demands of soft tissue approximation.

In drug delivery, it is processed into fibers, films, and microspheres designed to release active pharmaceutical ingredients over defined timeframes without requiring surgical removal of the device.

Medical device manufacturers use it to produce bone fixation pins, cardiovascular stents, and scaffolds for tissue engineering applications. Biotechnology researchers also select it as a matrix polymer.

It is frequently used for electrospun membranes in wound care and regenerative medicine platforms. Polydioxanone is supplied as a solid polymer, typically in pellet or powder form for industrial use.

Molecular weight grades are tailored to specific processing requirements such as melt spinning or electrospinning. Established grades include those meeting USP and Ph.Eur. standards for implantable use.

Resomer-branded grades are available with defined inherent viscosity specifications to support reproducible manufacturing outcomes. These materials ensure high performance in critical medical applications.