Polydioxanone

Polydioxanone (CAS 31621-87-1) is a biodegradable, absorbable polyester polymer. Also referenced commercially as Resomer X 210 and Resomer X 206S.

Where is Polydioxanone used?

• Absorbable monofilament sutures: flexibility and sustained tensile strength retention over several weeks for soft tissue approximation
• Drug delivery: fibers, films and microspheres releasing active pharmaceutical ingredients over defined timeframes without surgical removal
• Medical devices: bone fixation pins, cardiovascular stents and tissue engineering scaffolds
• Wound care and regenerative medicine: electrospun membranes
• It degrades predictably in biological environments through hydrolysis, serving as a controlled-release and structural material where temporary implantation is required.

Good to know: Grades include those meeting USP and Ph. Eur. standards for implantable use. Resomer-branded grades carry defined inherent viscosity specifications.

Commercial specifications

• Molecular weight grades tailored to melt spinning or electrospinning
• Inherent viscosity specifications defined for Resomer-branded grades