Propylene oxide

CAS Number
75-56-9
EC Number
200-879-2
Chemical Formula
C3H6O
Molecular Weight
58.08 g/mol
Abbreviation
PO

Description

Propylene oxide (CAS 75-56-9), commonly abbreviated as PO, is a reactive epoxide monomer and industrial solvent used across polymer manufacturing, sterilization, and chemical synthesis. Methyl oxirane is the form referenced in many technical and regulatory contexts as a distinct search term. Its primary commercial role is as a building block for polyols and propylene glycols.

PO is the key feedstock for polyether polyols used in polyurethane foam production. This covers rigid insulation panels, flexible seating, and various automotive interiors for industrial manufacturing. In food and pharmaceutical processing, it functions as a fumigant and sterilizing agent for spices and cocoa. It is also used for medical equipment where heat sterilization is not viable.

Propylene glycol, produced by hydration of PO, feeds into food-grade humectants and cosmetic carriers. It is also a primary component in modern antifreeze formulations and industrial coolants. In biotechnology, PO is used as a fixative and dehydration agent in electron microscopy sample preparation. It is supplied as a liquid in bulk quantities, typically via ISO tank containers.

Standard commercial grades include polymer-grade and technical-grade specifications. Purity levels are commonly at 99.5% or higher for polyol synthesis applications and chemical manufacturing. Buyers sourcing for food or pharmaceutical sterilization applications should confirm compliance with regional regulatory standards. Proper handling is required due to its low boiling point and volatility.

Other Names (Synonyms)

propene oxide|methyl oxirane|methyl ethylene oxide|2,3-epoxypropane|1,2-propylene oxide|1,2-epoxy propane|2-methyloxirane|Oxirane, methyl-|PO

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -112.13 °C
Boiling Point 34.23 °C
Density 0.8 g/cm³
Flash Point −35 °F
Appearance Propylene oxide is a colorless liquid. Ethereal odor.
Color Clear
Odor Ethereal; characteristic; sweet, alcoholyc; like natural gas.
Form Liquid
Water Solubility 40 g/100 mL (20 ºC)
Vapor Pressure 29.43 psi ( 55 °C)
Refractive Index n 20/D 1.366(lit.)
Log P 0.030

Documentation

Safety & Handling Learn More

Danger
GHS02· Flammable GHS06· Toxic GHS08· Health Hazard GHS07· Irritant GHS05· Corrosive

Hazard Statements

H224 Extremely flammable liquid and vapor
H302 Harmful if swallowed
H311 Toxic in contact with skin
H312 Harmful in contact with skin

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.

Trade & Regulatory

HS Code 29102000
UN Number 1280
ADR Class 3
Packing Group I
Storage Class 3 - Flammable liquids
WGK (Germany) 3
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