Ethylene oxide

CAS Number
75-21-8
EC Number
200-849-9
Chemical Formula
C2H4O
Molecular Weight
44.05 g/mol
Abbreviation
ETO

Description

Ethylene oxide (CAS 75-21-8), also known by the abbreviation ETO and the chemical name Oxirane, is a high-volume reactive monomer and sterilizing agent central to multiple industrial supply chains. It functions as a building block for polymerization reactions, a sterilant for heat-sensitive materials, and a chemical intermediate in the synthesis of downstream derivatives for various sectors.

In plastics and polymers, ETO is the primary monomer for producing ethylene glycols, polyethylene glycols, and ethoxylated surfactants used across detergent, textile, and personal care manufacturing. Pharmaceutical and medical device manufacturers rely on ETO gas sterilization to process single-use equipment, packaging, and instruments that cannot withstand heat or radiation during production.

In agriculture, ETO serves as a fumigant and sterilant for spices, herbs, and certain grain products where microbial load control is required before final processing and distribution to consumers. Biotechnology and life sciences operations use ETO to sterilize laboratory consumables and culture media components at scale, ensuring the integrity of sensitive research and development environments.

Ethylene oxide is supplied as a liquefied gas under pressure, typically in cylinders, drums, or bulk tank quantities. It is available in technical and pharmaceutical grades for diverse needs. Pharmaceutical-grade material meets USP and EP specifications for sterilization applications. Grade selection is a critical procurement decision given the regulatory requirements tied to each sector.

Other Names (Synonyms)

Oxirane|1,2-Epoxyethane|Anprolene|Oxyfume|Dimethylene oxide|LS 54 (EO-PO Block Copolymer)|ETO

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -111 °C
Boiling Point 10.7 °C @ Press: 760 Torr
Density 0.882 g/cm³ @ Temp: 10 °C
Flash Point <-17.7°C
Appearance Ethylene oxide is a colorless, compressed, liquefied gas or liquid (below 11℃). Sweet odor; the odor threshold is 50 ppm.
Odor Sweet odor detectable at 257 to 690 ppm
Form Colorless gas
Vapor Pressure 1095 mmHg at 20 °C
Refractive Index n 20/D 1.3597(lit.)
Log P -0.30

Documentation

Safety & Handling Learn More

Danger
GHS02· Flammable GHS05· Corrosive GHS06· Toxic GHS08· Health Hazard GHS04· Compressed Gas GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H220 Extremely flammable gas
H230 May react explosively even in the absence of air
H280 Contains gas under pressure; may explode if heated
H301 Toxic if swallowed

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P222 Do not allow contact with air.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.

Trade & Regulatory

HS Code 29101000
UN Number 2037
ADR Class 2.3
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 2
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