Genistein
Description
Genistein (CAS 446-72-0), also known as Prunetol and Genisteol, is a naturally occurring isoflavone extracted primarily from soy and other leguminous plants.
It functions as a phytoestrogen and antioxidant active across pharmaceutical, nutraceutical, and cosmetic applications. Buyers source it both as a purified reference-grade material and as a standardized botanical extract.
In nutraceutical and dietary supplement manufacturing, it is formulated into capsules, tablets, and functional foods targeting hormonal balance and bone health support for various consumer demographics.
Pharmaceutical developers use it as an intermediate in the synthesis of isoflavone-based compounds and as an active ingredient in investigational formulations requiring high purity and strict quality control.
Cosmetic formulators incorporate it into anti-aging creams and serums where its antioxidant activity supports skin surface stabilization and oxidative stress reduction for topical applications.
Food-grade applications include fortified beverages and soy-derived functional ingredients where standardized isoflavone content is a key quality parameter for manufacturers and industrial food processors.
The material is supplied as an off-white to pale yellow powder in technical and high-purity grades. Standardized extract forms, such as 85% HPLC, are commonly available for formulation work.
Reagent and reference-standard grades are also offered to support analytical and pharmaceutical development workflows, ensuring compliance with global chemical and nutritional safety regulations.
Physical Properties
| Melting Point | 301.5 °C (decomp) |
| Boiling Point | 333.35°C (rough estimate) |
| Density | 1.2319 (rough estimate) |
| Appearance | Yellow Crystalline Solid |
| Color | off-white |
| Form | powder |
| Water Solubility | insoluble |
| Refractive Index | 1.6000 (estimate) |
| Log P | 3.114 (est) |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29329900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
Prunetol|Genisteol|Differenol A|5,7,4'-Trihydroxyisoflavone|5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one|4',5,7-trihydroxyisoflavone|5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
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