Genistein

CAS Number
446-72-0
EC Number
207-174-9
Chemical Formula
C15H10O5
Molecular Weight
270.24 g/mol

Description

Genistein (CAS 446-72-0), also known as Prunetol and Genisteol, is a naturally occurring isoflavone extracted primarily from soy and other leguminous plants. It functions as a phytoestrogen and antioxidant active across pharmaceutical, nutraceutical, and cosmetic applications. Buyers source it both as a purified reference-grade material and as a standardized botanical extract.

In nutraceutical and dietary supplement manufacturing, it is formulated into capsules, tablets, and functional foods targeting hormonal balance and bone health support for various consumer demographics. Pharmaceutical developers use it as an intermediate in the synthesis of isoflavone-based compounds and as an active ingredient in investigational formulations requiring high purity and strict quality control.

Cosmetic formulators incorporate it into anti-aging creams and serums where its antioxidant activity supports skin surface stabilization and oxidative stress reduction for topical applications. Food-grade applications include fortified beverages and soy-derived functional ingredients where standardized isoflavone content is a key quality parameter for manufacturers and industrial food processors.

The material is supplied as an off-white to pale yellow powder in technical and high-purity grades. Standardized extract forms, such as 85% HPLC, are commonly available for formulation work. Reagent and reference-standard grades are also offered to support analytical and pharmaceutical development workflows, ensuring compliance with global chemical and nutritional safety regulations.

Other Names (Synonyms)

Prunetol|Genisteol|Differenol A|5,7,4'-Trihydroxyisoflavone|5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one|4',5,7-trihydroxyisoflavone|5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 301.5 °C (decomp)
Boiling Point 333.35°C (rough estimate)
Density 1.2319 (rough estimate)
Appearance Yellow Crystalline Solid
Color off-white
Form powder
Water Solubility insoluble
Refractive Index 1.6000 (estimate)
Log P 3.114 (est)

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.

Trade & Regulatory

HS Code 29329900
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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