Genistein

CAS Number
446-72-0
EC Number
207-174-9

What is Genistein?

Genistein (CAS 446-72-0), also known as Prunetol and Genisteol, is a naturally occurring isoflavone extracted primarily from soy and other leguminous plants.

Where is Genistein used?

  • Pharmaceutical: intermediate in isoflavone-based compound synthesis and active ingredient in investigational formulations
  • Nutraceutical and dietary supplements: capsules, tablets, and functional foods for hormonal balance and bone health support
  • Cosmetics: anti-aging creams and serums
  • Food-grade: fortified beverages and soy-derived functional ingredients
  • It functions as a phytoestrogen and antioxidant active.

Good to know: Available as purified reference-grade material or standardized botanical extract. Standardized isoflavone content is a key quality parameter.

Commercial specifications

  • Technical and high-purity grades
  • Standardized extract forms such as 85% HPLC

Other Names (Synonyms)

Prunetol|Genisteol|Differenol A|5,7,4'-Trihydroxyisoflavone|5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one|4',5,7-trihydroxyisoflavone|5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one

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What are the physical properties of Genistein?

Melting Point 301.5 °C (decomp)
Boiling Point 333.35°C (rough estimate)
Density 1.2319 (rough estimate)
Appearance Yellow Crystalline Solid
Color off-white
Form powder
Water Solubility insoluble
Refractive Index 1.6000 (estimate)
Log P 3.114 (est)

How is Genistein classified and handled safely? Learn More

Warning
GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to Genistein?

HS Code 29329900
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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