SoleChem

Apigenin

CAS
520-36-5
EC
208-292-3
Mol. Weight
270.24 g/mol

Description

Apigenin (CAS 520-36-5), also known commercially as Apigenol, is a naturally derived flavonoid extracted primarily from chamomile, parsley, and celery. It functions as a bioactive antioxidant ingredient across pharmaceutical, nutraceutical, and cosmetic formulations.

In dietary supplement manufacturing, this compound is incorporated into capsules, tablets, and functional beverages targeting antioxidant and wellness positioning. Cosmetic formulators use it as an active ingredient in anti-aging and skin-brightening topicals.

Its antioxidant capacity supports product claims around oxidative stress protection in high-end skincare lines. Food and beverage producers source it as a natural colorant and functional additive, particularly in products where clean-label botanical ingredients are advantageous.

Pharmaceutical researchers and contract manufacturers also use it as a reference standard or active botanical extract in preclinical and formulation development programs. This versatility makes it a staple for R&D departments across multiple industries.

The product is supplied as a fine yellow powder, typically derived from chamomile flower extract or synthesized for higher purity applications. Standard market grades include 98%+ purity (HPLC) for pharmaceutical and research use.

Lower-purity botanical extract forms are available for nutraceutical and cosmetic applications where full-spectrum profiles are preferred. Packaging ranges from small quantities for R&D procurement to bulk quantities suited for commercial-scale formulation.

Our supply chain ensures that all batches meet rigorous internal quality standards. We provide comprehensive documentation including certificates of analysis and safety data sheets to support your regulatory compliance and manufacturing requirements.

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Physical Properties

Melting Point 347.5 °C
Boiling Point 333.35°C (rough estimate)
Density 1.2319 (rough estimate)
Appearance Pale Yellow Crystalline Solid
Color yellow
Form powder
Refractive Index 1.6000 (estimate)
Log P 3.020

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H412 Harmful to aquatic life with long lasting effects
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29329900
WGK (Germany) 3

Documentation

Other Names

5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one|Versulin|Apigenol|4',5,7-Trihydroxyflavone|Apigenine|Spigenin|C.I. Natural Yellow 1|5,7,4'-Trihydroxyflavone

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