Apigenin

CAS Number
520-36-5
EC Number
208-292-3

What is Apigenin?

Apigenin (CAS 520-36-5), also known commercially as Apigenol, is a naturally derived flavonoid extracted primarily from chamomile, parsley, and celery.

Where is Apigenin used?

  • Pharmaceutical, nutraceutical and cosmetic formulations: bioactive antioxidant ingredient
  • Dietary supplements: capsules, tablets and functional beverages for antioxidant and wellness positioning
  • Cosmetics: active in anti-aging and skin-brightening topicals
  • Food and beverage: natural colorant and functional additive for clean-label botanical products
  • Pharmaceutical research: reference standard or active botanical extract in preclinical and formulation development
  • It is a staple for R&D departments across multiple industries.

Commercial specifications

  • 98%+ purity (HPLC) for pharmaceutical and research use
  • Lower-purity botanical extract forms for nutraceutical and cosmetic applications
  • Packaging from small R&D quantities to bulk commercial-scale quantities
  • Certificates of analysis and safety data sheets provided

Other Names (Synonyms)

5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one|Versulin|Apigenol|4',5,7-Trihydroxyflavone|Apigenine|Spigenin|C.I. Natural Yellow 1|5,7,4'-Trihydroxyflavone

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What are the physical properties of Apigenin?

Melting Point 347.5 °C
Boiling Point 333.35°C (rough estimate)
Density 1.2319 (rough estimate)
Appearance Pale Yellow Crystalline Solid
Color yellow
Form powder
Refractive Index 1.6000 (estimate)
Log P 3.020

How is Apigenin classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H412 Harmful to aquatic life with long lasting effects

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.

Which trade and regulatory codes apply to Apigenin?

HS Code 29329900
WGK (Germany) 3
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