Hesperidin
Description
Hesperidin (CAS 520-26-3), also known as Cirantin or Hesperetin 7-rutinoside, is a flavonoid glycoside sourced primarily from citrus peel. It is used across pharmaceutical, nutraceutical, and cosmetic formulations for its antioxidant activity.
This versatile compound provides essential support for vascular and cellular protection in various finished products. In dietary supplements and functional foods, it is formulated into capsules, tablets, and fortified beverages.
These applications typically target circulatory health and general antioxidant support for consumers. Pharmaceutical manufacturers incorporate it into veinotonic preparations and combination products alongside diosmin for standardized profiles.
Cosmetic and personal care formulators use it in serums and creams to stabilize formulations against oxidative degradation. It also supports skin-conditioning claims while enhancing the overall stability of the topical product.
In nutraceutical blends, it is commonly paired with vitamin C to enhance bioavailability and broaden the antioxidant profile. This synergy is highly valued in the production of high-quality health and wellness supplements.
The material is supplied as a fine yellow to off-white powder, with purity grades typically ranging from 90% to 98% by HPLC. Standard commercial grades conform to USP, Ph. Eur., and food-grade specifications.
High-purity pharmaceutical grades are available for regulated drug product manufacturing. Bulk supply is available in kilogram and metric ton quantities, standardized from sweet orange or bitter orange sources.
Physical Properties
| Melting Point | 262 °C |
| Boiling Point | 930 °C |
| Density | 1.3290 (rough estimate) |
| Appearance | light brown powder |
| Color | light brown |
| Form | Powder |
| Water Solubility | Insoluble in water. Soluble in organic solvents such as DMSO. |
| Refractive Index | 1.5940 (estimate) |
| Log P | 0.3 at 25℃ |
Trade & Regulatory
| HS Code | 29389000 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
Cirantin|(S)-(-)-hesperidin|Hesperetin 7-rutinoside|Ciratin|Hesperetin 7-rhamnoglucoside|DIOSVEIN|Flavanone, 3′,5,7-trihydroxy-4′-methoxy-, 7-(6-O-α-L-rhamnosyl-D-glucoside)
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