Neohesperidin dihydrochalcone

Neohesperidin dihydrochalcone (CAS 20702-77-6), commonly known as NHDC, is a semi-synthetic sweetener derived from citrus bioflavonoids. Food-grade quality compliant with EU specifications (E 959); FEMA 3811 for flavoring use in the United States.

Where is Neohesperidin dihydrochalcone used?

• Food and beverage: high-potency sweetener and flavor modifier in reduced-sugar and sugar-free formulations
• Confectionery and dairy: bulk sweetener replacement at 15–50 ppm
• Pharmaceutical oral preparations and functional foods: bitterness masking
• Oral hygiene: toothpastes and mouthwashes
• It acts as a flavor enhancer and sweetness synergist with high-intensity sweeteners such as steviol glycosides.
• Effective at masking the bitter taste of other citrus compounds, including limonin and naringin.
• Applied to food and beverage products including ketchup, mayonnaise, yogurt and ice cream.

Good to know: At concentrations far below those of sucrose, it delivers intense sweetness with a characteristic cooling, menthol-like aftertaste. Synergy with other high-intensity sweeteners allows formulators to reduce the total sweetener load.

Formulation notes

• In food, used as a flavour enhancer at concentrations of around 4-5 ppm.

Typical specification

• Approximately 1000 to 1800 times as sweet as sucrose.
• Assay content: not less than 98.0%.
• Loss on drying: not more than 5.0%.
• Particle size: not less than 98% passes through 80 mesh.

Regulatory status

• EFSA derived an acceptable daily intake (ADI) of 20 mg/kg body weight per day for E 959.
• Included in both the European Pharmacopoeia and the United States Pharmacopoeia for use as an excipient in drug products.

Storage, packaging and handling

• Store in original unopened containers in a cool, dry place before use, away from direct sunlight, heat and moisture.
• Can remain food-safe for up to five years when stored under optimal conditions.

Frequently asked questions about Neohesperidin dihydrochalcone

What purity and impurity limits apply to neohesperidin dihydrochalcone?

EU specifications require a purity assay of not less than 96% chemical purity. Heavy metals are limited to not more than 10.00 ppm.

What is the water solubility of neohesperidin dihydrochalcone at 20°C?

It is slightly soluble in water at 20°C, with a solubility of 230 mg/L.

How does neohesperidin dihydrochalcone act as a flavour enhancer?

It acts as a flavour enhancer by increasing fruit and cocoa derivative flavours.

Technical content is compiled and updated by the SoleChem product team from public technical sources; the certificate of analysis (COA) governs product-specific specifications.