Glycyrrhizin

CAS Number
1405-86-3
EC Number
215-785-7

What is Glycyrrhizin?

Glycyrrhizin (CAS 1405-86-3), also known as glycyrrhizinic acid and classified as E958 in food applications, is the principal bioactive triterpene glycoside extracted from licorice root.

Where is Glycyrrhizin used?

  • Food and beverage: intense sweetener, roughly 50 times sweeter than sucrose, masking bitter off-notes in functional ingredients, protein blends and nutraceutical formulations
  • Pharmaceuticals: excipient and flavor-masking agent in syrups, lozenges and chewable tablets
  • Personal care: skin-soothing serums, toners and brightening formulations, supporting moisture retention and stabilizing actives against oxidative degradation
  • Confectionery and tobacco processing rely on it as a flavor enhancer and humectant to control texture.

Good to know: Available as the ammoniated form and as the free acid. Supply meets USP, BP and cosmetic-grade requirements.

Commercial specifications

  • Purity typically 95% to 98% depending on application

Other Names (Synonyms)

Glycyrrhizinic acid|Glycyron|Glizigen|18-beta-Glycyrrhizic acid|Glycyrrhizic acid|potenlini|beta-Glycyrrhizin|Glycyrrhetinic acid glycoside|E958

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What are the physical properties of Glycyrrhizin?

Melting Point 220 °C (decomp)
Boiling Point 681.01°C (rough estimate)
Density 1.1442 (rough estimate)
Color White to Light Yellow
Odor at 100.00 %. mild spicy
Form Solid
Refractive Index 61 ° (C=1.5, EtOH)
Log P 4.64

Which trade and regulatory codes apply to Glycyrrhizin?

HS Code 29389000
WGK (Germany) 3
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