SoleChem

Glabridin

Flavors & Fragrances Personal Care & Cosmetics
CAS
59870-68-7
EC
N/A
Mol. Weight
324.4 g/mol

Description

Glabridin (CAS 59870-68-7) is the primary bioactive isoflavonoid extracted from licorice root, where it occurs as the dominant polyphenol in the hydrophobic fraction. In commercial formulation, it functions as a skin-brightening active and antioxidant.

This compound serves as a UV-stabilizing ingredient across cosmetic and pharmaceutical product lines. In topical skincare, it is formulated into serums, creams, and spot-treatment products targeting hyperpigmentation and uneven skin tone.

The ingredient inhibits melanin synthesis pathways relevant to cosmetic efficacy claims. Suncare formulators incorporate it as a secondary UV-stabilizing component alongside primary filters to improve photostability of finished SPF products.

In functional food and nutraceutical applications, it is used in antioxidant-positioned supplements and standardized licorice extracts. Buyers require documented polyphenol content for these specific health and wellness applications.

Pharmaceutical researchers and contract manufacturers source it as a reference standard or active ingredient for topical dermatological preparations. It is supplied as an off-white to pale yellow powder for various industrial uses.

The material is typically standardized to 90%, 95%, or 98% purity by HPLC. It is available in both cosmetic-grade and research-grade specifications, with documentation suited to EU cosmetic regulation dossiers or pharmaceutical development files.

Packaging ranges from small quantities for R&D through to kilogram-scale lots for commercial formulation. Our supply chain ensures consistent quality and purity levels that meet rigorous international manufacturing requirements.

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Physical Properties

Melting Point 238-240 °C
Boiling Point 518.6±50.0 °C(Predicted)
Density 1.257±0.06 g/cm3(Predicted)
Flash Point 267°C
Color white to light brown
Form powder
Log P 4.260 (est)

Trade & Regulatory

HS Code 29329990
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

4-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol|HOC5567T41|2H,8H-Benzo[1,2-b:3,4-b′]dipyran, 1,3-benzenediol deriv.|Glycyrrhiza Glabra Root Extract

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