Glabridin
What is Glabridin?
Glabridin (CAS 59870-68-7) is the primary bioactive isoflavonoid extracted from licorice root, where it occurs as the dominant polyphenol in the hydrophobic fraction.
Where is Glabridin used?
- Cosmetic formulation: skin-brightening active and antioxidant
- Cosmetics and pharmaceuticals: UV-stabilizing ingredient
- Topical skincare: serums, creams, and spot-treatment products targeting hyperpigmentation and uneven skin tone
- It inhibits melanin synthesis pathways relevant to cosmetic efficacy claims.
- Suncare: secondary UV-stabilizing component alongside primary filters to improve photostability of finished SPF products
- Functional food and nutraceuticals: antioxidant-positioned supplements and standardized licorice extracts
- Pharmaceuticals: reference standard or active ingredient for topical dermatological preparations
Good to know: Buyers require documented polyphenol content for health and wellness applications. The material is typically standardized to 90%, 95%, or 98% purity by HPLC, with cosmetic-grade and research-grade specifications and documentation suited to EU cosmetic regulation dossiers or pharmaceutical development files.
Commercial specifications
- Standardized to 90%, 95%, or 98% purity by HPLC
- Documentation suited to EU cosmetic regulation dossiers or pharmaceutical development files
- Packaging from small R&D quantities to kilogram-scale lots
Other Names (Synonyms)
4-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol|HOC5567T41|2H,8H-Benzo[1,2-b:3,4-b′]dipyran, 1,3-benzenediol deriv.|Glycyrrhiza Glabra Root Extract