Glabridin

CAS Number
59870-68-7
EC Number
N/A

What is Glabridin?

Glabridin (CAS 59870-68-7) is the primary bioactive isoflavonoid extracted from licorice root, where it occurs as the dominant polyphenol in the hydrophobic fraction.

Where is Glabridin used?

  • Cosmetic formulation: skin-brightening active and antioxidant
  • Cosmetics and pharmaceuticals: UV-stabilizing ingredient
  • Topical skincare: serums, creams, and spot-treatment products targeting hyperpigmentation and uneven skin tone
  • It inhibits melanin synthesis pathways relevant to cosmetic efficacy claims.
  • Suncare: secondary UV-stabilizing component alongside primary filters to improve photostability of finished SPF products
  • Functional food and nutraceuticals: antioxidant-positioned supplements and standardized licorice extracts
  • Pharmaceuticals: reference standard or active ingredient for topical dermatological preparations

Good to know: Buyers require documented polyphenol content for health and wellness applications. The material is typically standardized to 90%, 95%, or 98% purity by HPLC, with cosmetic-grade and research-grade specifications and documentation suited to EU cosmetic regulation dossiers or pharmaceutical development files.

Commercial specifications

  • Standardized to 90%, 95%, or 98% purity by HPLC
  • Documentation suited to EU cosmetic regulation dossiers or pharmaceutical development files
  • Packaging from small R&D quantities to kilogram-scale lots

Other Names (Synonyms)

4-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol|HOC5567T41|2H,8H-Benzo[1,2-b:3,4-b′]dipyran, 1,3-benzenediol deriv.|Glycyrrhiza Glabra Root Extract

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What are the physical properties of Glabridin?

Melting Point 238-240 °C
Boiling Point 518.6±50.0 °C(Predicted)
Density 1.257±0.06 g/cm3(Predicted)
Flash Point 267°C
Color white to light brown
Form powder
Log P 4.260 (est)

Which trade and regulatory codes apply to Glabridin?

HS Code 29329990
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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