Glabridin
Description
Glabridin (CAS 59870-68-7) is the primary bioactive isoflavonoid extracted from licorice root, where it occurs as the dominant polyphenol in the hydrophobic fraction. In commercial formulation, it functions as a skin-brightening active and antioxidant.
This compound serves as a UV-stabilizing ingredient across cosmetic and pharmaceutical product lines. In topical skincare, it is formulated into serums, creams, and spot-treatment products targeting hyperpigmentation and uneven skin tone.
The ingredient inhibits melanin synthesis pathways relevant to cosmetic efficacy claims. Suncare formulators incorporate it as a secondary UV-stabilizing component alongside primary filters to improve photostability of finished SPF products.
In functional food and nutraceutical applications, it is used in antioxidant-positioned supplements and standardized licorice extracts. Buyers require documented polyphenol content for these specific health and wellness applications.
Pharmaceutical researchers and contract manufacturers source it as a reference standard or active ingredient for topical dermatological preparations. It is supplied as an off-white to pale yellow powder for various industrial uses.
The material is typically standardized to 90%, 95%, or 98% purity by HPLC. It is available in both cosmetic-grade and research-grade specifications, with documentation suited to EU cosmetic regulation dossiers or pharmaceutical development files.
Packaging ranges from small quantities for R&D through to kilogram-scale lots for commercial formulation. Our supply chain ensures consistent quality and purity levels that meet rigorous international manufacturing requirements.
Physical Properties
| Melting Point | 238-240 °C |
| Boiling Point | 518.6±50.0 °C(Predicted) |
| Density | 1.257±0.06 g/cm3(Predicted) |
| Flash Point | 267°C |
| Color | white to light brown |
| Form | powder |
| Log P | 4.260 (est) |
Trade & Regulatory
| HS Code | 29329990 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
4-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol|HOC5567T41|2H,8H-Benzo[1,2-b:3,4-b′]dipyran, 1,3-benzenediol deriv.|Glycyrrhiza Glabra Root Extract
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