SoleChem

Glycyrrhetinic acid

CAS
471-53-4
EC
207-444-6
Mol. Weight
470.7 g/mol

Description

Glycyrrhetinic acid (CAS 471-53-4), also known as uralenic acid, is a pentacyclic triterpenoid derived from licorice root extract. In personal care and cosmetics, it functions as a skin-conditioning active.

In flavoring applications, it contributes to the characteristic licorice taste profile of finished products. In cosmetic formulations, it is used in anti-inflammatory creams, serums, and spot-treatment products.

Formulators incorporate it into whitening and brightening preparations where it acts as a tyrosinase modulator. This helps to reduce the appearance of hyperpigmentation and redness in various skin types.

In the flavor industry, it is used as a flavoring agent and acidulant in confectionery and oral care products. It is also utilized in tobacco flavoring systems where a licorice character is required.

It appears in topical pharmaceutical preparations as a functional active in formulations addressing minor skin irritation. The material is supplied as a white to off-white crystalline powder for industrial use.

It is available in cosmetic-grade and pharmaceutical-grade specifications, with purity levels typically ranging from 95% to 98% by HPLC. These standards ensure high performance in sensitive applications.

Bulk quantities are offered in kilogram and multi-kilogram packaging to suit both development-scale and commercial production requirements. We ensure consistent quality for all global manufacturing needs.

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Physical Properties

Melting Point 296 °C
Boiling Point 687.4 °C
Density 0.9967 (rough estimate)
Appearance white or greyish-white crystalline powder
Color White to off-white
Form Crystalline Powder
Water Solubility SOLUBLE IN ACETIC ACID
Vapor Pressure 10-220Pa at 20-50℃
Refractive Index 162 ° (C=1, MeOH)
Log P 4.5 at 20℃

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H302 Harmful if swallowed
H319 Causes serious eye irritation
Precautionary Statements
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P330 Rinse mouth.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29189900
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

Uralenic acid|Glycyrrhetic Acid|beta-Glycyrrhetic acid|b-Glycyrrhetic acid|alpha-Glycyrrhetinic acid|a-Glycyrrhetinic acid|3b-Hydroxy-11-oxoolean-12-en-30-oic acid|3b-Hydroxy-11-oxoolean-12-en-30-oate

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