Nordihydroguaiaretic acid

Nordihydroguaiaretic acid (CAS 500-38-9), commonly identified in procurement as NDGA, is a naturally derived phenolic antioxidant extracted from the creosote bush. It functions as a potent lipid oxidation inhibitor and stabilizer across food, pharmaceutical, and cosmetic manufacturing. In food processing, NDGA delays rancidity in fats, oils, and lipid-rich formulations where oxidative stability directly affects shelf life and product quality. Pharmaceutical formulators incorporate it as an antioxidant excipient to protect active ingredients.

It is used to protect lipid-based drug delivery systems from oxidative degradation during storage. In personal care and cosmetic manufacturing, it is used in creams, lotions, and suncare formulations for both antioxidant protection and UV stabilization. Research and specialty chemical buyers also source NDGA as a reference standard or active compound in investigational formulations targeting oxidative stress pathways. This versatile compound is essential for maintaining the integrity of sensitive chemical structures.

Nordihydroguaiaretic acid is supplied as a fine crystalline powder. It is available in research-grade and technical-grade specifications, with high-purity grades typically exceeding ninety-eight percent purity for specialized use. High-purity grades are offered for pharmaceutical and analytical applications. Packaging ranges from small quantities for laboratory and formulation development to bulk supply for industrial use, ensuring flexibility for various procurement needs.