Nordihydroguaiaretic acid
What is Nordihydroguaiaretic acid?
Nordihydroguaiaretic acid (CAS 500-38-9), commonly identified in procurement as NDGA, is a naturally derived phenolic antioxidant extracted from the creosote bush.
Where is Nordihydroguaiaretic acid used?
- Food processing: lipid oxidation inhibitor and stabilizer that delays rancidity in fats, oils, and lipid-rich formulations
- Pharmaceutical: antioxidant excipient protecting active ingredients and lipid-based drug delivery systems from oxidative degradation
- Personal care and cosmetics: antioxidant protection and UV stabilization in creams, lotions, and suncare formulations
- Research and specialty chemical buyers source NDGA as a reference standard or active compound in investigational formulations targeting oxidative stress pathways.
Commercial specifications
- High-purity grades for pharmaceutical and analytical applications
- Packaging from small laboratory quantities to bulk industrial supply
Other Names (Synonyms)
NDGA|nordihydroguaretic acid|2,3-bis(3,4-dihydroxybenzyl)butane|RefChem:854717|4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol|Norhydroguaiaretic acid|Norguaiaretic acid, dihydro-|1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-