Caffeic acid

CAS Number
331-39-5
EC Number
206-361-2

What is Caffeic acid?

Caffeic acid (CAS 331-39-5), also known as 3,4-Dihydroxycinnamic Acid, is a hydroxycinnamic acid naturally occurring in many plants.

Where is Caffeic acid used?

  • Pharmaceutical manufacturing: intermediate in synthesis of active compounds and antioxidant-focused dietary supplement formulations
  • Food and beverage: natural antioxidant extending shelf life and protecting against oxidative degradation
  • Personal care and cosmetics: UV-stabilizing properties in sunscreen boosters and anti-aging topical products
  • Nutraceutical formulators include it in standardized botanical extracts where polyphenol content is a defined quality parameter.

Commercial specifications

  • Purity levels of 98% and above are standard for pharmaceutical and nutraceutical applications.
  • Documentation such as COA and HPLC testing is commonly provided to ensure compliance with global industry benchmarks.

Other Names (Synonyms)

Cichoric acid|caffeic acid (trans from)|3,4-Dihydroxycinnamic Acid|3,4-Dihydroxy-trans-cinnamate|3,4-Dihydroxybenzeneacrylic acid|2-propenoic acid, 3-(3,4-dihydroxyphenyl)-|3-(3,4-Dihydroxyphenyl)-2-propenoic acid|(E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid

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What are the physical properties of Caffeic acid?

Melting Point 225 °C (decomp)
Boiling Point 272.96°C (rough estimate)
Density 1.2933 (rough estimate)
Appearance Light yellow to greenish-yellow powder
Color yellow to tan
Form powder
Water Solubility soluble in hot water
Refractive Index 1.4500 (estimate)
Log P 1.150

How is Caffeic acid classified and handled safely? Learn More

Warning
GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H351 Suspected of causing cancer
H361 Suspected of damaging fertility or the unborn child

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to Caffeic acid?

HS Code 29182990
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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