Organic Acids
REACH
Vanillic acid
CAS Number
121-34-6
EC Number
204-466-8
FEMA Number
FEMA 3988
What is Vanillic acid?
Vanillic acid (CAS 121-34-6), also identified by its FEMA number 3988, is a naturally derived phenolic acid. Also known as vanillate in salt form.
Where is Vanillic acid used?
- Pharmaceutical manufacturing: intermediate
- Drug formulations: antioxidant stabilization against oxidative degradation
- Food and beverage: flavoring adjunct and oxidation inhibitor
- Cosmetics and personal care: antioxidant and UV-stabilizing agent in skin-care products
- Preservative booster in multi-ingredient systems, extending shelf life without high active concentrations
Good to know: Standard commercial grades include food-grade material meeting FEMA 3988 specifications and pharmaceutical-grade material, aligned with USP or technical-grade standards depending on end-use requirements.
Commercial specifications
- Food-grade material meeting FEMA 3988 specifications
- Pharmaceutical-grade material aligned with USP or technical-grade standards
- Packaging in kilogram quantities through bulk metric-ton volumes
Other Names (Synonyms)
Protocatechuic acid, 3-methyl ether|Vanillate|p-Vanillic acid|p-Vanillate|m-Anisic acid, 4-hydroxy-|Benzoic acid, 4-hydroxy-3-methoxy-|Acide vanillique|4-Hydroxy-m-Anisic acid
What are the physical properties of Vanillic acid?
Melting Point 211.5 °C
Boiling Point 257.07°C (rough estimate)
Density 1.44 g/cm³ @ Temp: 25 °C
Appearance white odourless crystals or powder
Color Clear colorless to brown, may darken during storage
Odor at 100.00 %. dairy milky custard creamy powdery vanilla bean
Form Liquid
Water Solubility Soluble in water, alcohol and ether.
Refractive Index 1.5090 (estimate)
Log P 1.30
How is Vanillic acid classified and handled safely? Learn More
Warning
GHS07· Irritant
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
Which trade and regulatory codes apply to Vanillic acid?
HS Code 29189090
Storage Class 11 - Combustible Solids
WGK (Germany) 1