Crocetin

CAS Number
27876-94-4
EC Number
248-708-0

What is Crocetin?

Crocetin (CAS 27876-94-4) is a natural carotenoid dicarboxylic acid derived primarily from saffron and gardenia fruit, where it occurs as the aglycone core of crocin pigments.

Where is Crocetin used?

  • Food and beverage: natural yellow-to-orange colorant where synthetic dye replacement is a priority
  • Nutraceutical and dietary supplement manufacturing: incorporated into capsules and softgels for cognitive support and sleep quality positioning
  • Cosmetics: antioxidant activity in premium skincare serums and creams
  • Pharmaceutical research: active botanical extract for investigational oral and topical preparations
  • It also functions as a natural colorant and antioxidant active.

Commercial specifications

  • Standardized extract form with purity levels ranging from around 90% to 98%+ by HPLC
  • Synthetic and natural grades
  • Specification documentation commonly includes heavy metal testing and residual solvent data

Other Names (Synonyms)

trans-crocetin|8,8'-diapocarotenedioic acid|8,8'-diapo-psi,psi-carotenedioic acid|8,8'-diapo-8,8'-carotenedioic acid|Transcrocetinic acid|2,4,6,8,10,12,14-Hexadecaheptaenedioic acid, 2,6,11,15-tetramethyl-, (all-E)-

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What are the physical properties of Crocetin?

Melting Point 286 °C
Boiling Point 386.14°C (rough estimate)
Density 1.0786 (rough estimate)
Appearance Red, rhomboid crystals.Soluble in pyridine and dilute sodium hydroxide; slightly soluble in water and organic solvents. Combustible.
Color Red to Very Dark Red
Form Solid
Refractive Index 1.4434 (estimate)
Log P 4.312 (est)

How is Crocetin classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H317 May cause an allergic skin reaction

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.

Which trade and regulatory codes apply to Crocetin?

HS Code 29171900
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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