Synephrine

Synephrine (CAS 94-07-5), also known as p-synephrine, is a naturally occurring alkaloid extracted primarily from bitter orange. It functions as an adrenergic agonist active ingredient in pharmaceutical formulations. The compound is used across nutraceutical and cosmetic applications as a bioactive compound. In pharmaceutical manufacturing, it serves as an active ingredient in preparations targeting nasal congestion and circulatory support.

Its adrenergic activity drives formulation decisions for various medical applications. Nutraceutical producers incorporate it into weight management and sports nutrition products as a stimulant-adjacent botanical extract. This application is particularly common following restrictions on ephedrine-based ingredients. In topical cosmetic formulations, it is used for its skin-firming and anti-cellulite positioning in slimming creams.

Contract manufacturers also source it as a pharmaceutical intermediate for synthesizing structurally related adrenergic compounds. Synephrine is supplied as a white to off-white crystalline powder. Standard commercial grades include pharmaceutical-grade material meeting USP or BP specifications. Technical-grade material is also available for industrial synthesis and chemical processing.

High-purity extracts standardized from Citrus aurantium are available for nutraceutical and dietary supplement applications. These extracts ensure consistent potency and quality for global manufacturing standards.