Sennosides

Sennosides (CAS 85085-71-8), also marketed under the trade name Glysennid, are anthraquinone glycosides extracted from Senna plants and standardized for use as active pharmaceutical ingredients.

They function as stimulant laxatives by promoting colonic motility, making them a primary active in regulated OTC and prescription bowel-management products for global distribution.

In pharmaceutical manufacturing, sennosides are the active ingredient in tablet, capsule, and syrup formulations targeting constipation relief and bowel preparation prior to medical procedures.

Standardized sennoside extracts are incorporated into combination laxative products alongside bulking agents or stool softeners for enhanced clinical effect in various therapeutic applications.

In dietary supplement and functional food categories, sennoside-standardized senna leaf and pod extracts are used in herbal laxative teas, softgels, and wellness blends sold through retail channels.

Contract formulators sourcing for private-label OTC products typically specify sennoside content by percentage to meet pharmacopoeial potency requirements and ensure consistent product efficacy.

Sennosides are supplied as a dry powder, typically standardized to defined sennoside A and B content. Material is available to USP, BP, and Ph. Eur. specifications for buyers.

Documented COA and microbial testing are standard for pharmaceutical-grade supply. Food and supplement-grade material is also available for herbal extract applications requiring lower thresholds.