Cascara sagrada bark extract

CAS Number
84650-55-5
FEMA Number
FEMA 2253

What is Cascara sagrada bark extract?

Cascara sagrada bark extract (CAS 84650-55-5), also referenced commercially as Rhamnus purshiana extract, is a botanical extract derived from the aged bark of the cascara buckthorn tree.

Where is Cascara sagrada bark extract used?

  • Pharmaceutical formulations: active botanical ingredient in laxative preparations, with anthraquinone glycoside content driving the physiological effect
  • Food and beverage: bittering and flavoring agent in bitters, liqueurs and specialty soft drinks
  • Dietary supplements: capsules, tablets and liquid tonics for digestive health positioning
  • Preservation-oriented formulations use its antimicrobial activity for product stabilization and shelf-life extension.

Good to know: Pharmaceutical-grade material is typically standardized to hydroxyanthracene glycoside content to meet defined potency specifications; food-grade supply conforms to FEMA 2253 status.

Commercial specifications

  • Standardized and non-standardized grades
  • Pharmaceutical grade standardized to hydroxyanthracene glycoside content
  • Food grade conforms to FEMA 2253

Other Names (Synonyms)

Rhamnus purshiana, ext.

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