Milk thistle extract

CAS Number
84604-20-6
EC Number
283-298-7
Chemical Formula
Unspecified
Molecular Weight
482.4 g/mol

Description

Milk thistle extract (CAS 84604-20-6), derived from Silybum marianum, is a standardized botanical extract concentrated in silymarin flavonolignans. It functions as a plant-based antioxidant active across nutraceutical, pharmaceutical, and cosmetic formulations. Buyers typically source it against defined silymarin content, making standardization the primary procurement specification. In dietary supplements and functional foods, it is formulated into capsules, softgels, and tablets targeting liver support positioning.

This extract represents one of the highest-volume botanical supplement categories globally. Pharmaceutical manufacturers use silymarin-standardized grades as an intermediate in hepatoprotective drug formulations, particularly in European and Asian markets. In these regions, liver-related indications are formally approved for medical use. In cosmetics and personal care, it is incorporated into anti-aging serums, facial creams, and scalp treatments where antioxidant actives are required.

These formulations protect against oxidative stress in the formulation matrix. Sports nutrition and wellness brands also use it in detox and cleanse product lines as a label-active botanical ingredient for health-conscious consumers. Milk thistle extract is supplied as a fine powder, typically standardized to 70%, 80%, or 95% silymarin content by HPLC. Food-grade and USP-grade specifications are available for supplement and pharmaceutical applications.

Bulk supply is standard in kilogram to metric ton quantities to meet industrial demand. Water-soluble and oil-dispersible variants are available for specific formulation needs across various delivery systems.

Other Names (Synonyms)

Silybum marianum, ext.|Silybum marianum|3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one|Silymarin

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Density 1.144
Vapor Pressure 0.004Pa at 20℃

Safety & Handling (Learn More)

Warning
GHS08· Health Hazard

Hazard Statements

H361 Suspected of damaging fertility or the unborn child
H373 May causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P318 IF exposed or concerned, get medical advice.
P319 Get medical advice/attention if you feel unwell.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.

Trade & Regulatory

HS Code 2932996560

Documentation

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