L-5-Hydroxytryptophan
Description
L-5-Hydroxytryptophan (CAS 4350-09-8), commonly known as 5-HTP and commercially sourced as Oxitriptan or Griffonia Seed Extract, is a naturally occurring amino acid precursor used across pharmaceutical, nutraceutical, and functional food manufacturing.
It is commercially extracted from the seeds of Griffonia simplicifolia and serves as a direct biosynthetic precursor to serotonin, making it a primary active ingredient in mood and sleep support formulations.
In nutraceutical manufacturing, 5-HTP is the core active in dietary supplement capsules and tablets targeting sleep quality, appetite regulation, and mood balance. Functional food and beverage formulators incorporate it into fortified products.
Pharmaceutical-grade material is used in clinical and OTC product development, particularly in markets where Oxitriptan is recognized as an established API. It meets rigorous quality standards for global distribution.
Cosmetic formulators have adopted it in premium skincare lines for its antioxidant activity, positioning it in anti-aging serums and moisturizing treatments. This versatility makes it a valuable raw material for diverse industries.
5-HTP is supplied as a fine white to off-white powder. Standard commercial grades include food-grade and pharmaceutical-grade specifications, with purity levels typically at 98% or higher by HPLC analysis.
Material derived from Griffonia seed extract is the dominant commercial form and is available with supporting documentation for botanical traceability. Our supply chain ensures consistent quality and reliable lead times for bulk orders.
Physical Properties
| Melting Point | 273 °C (decomp) |
| Boiling Point | 361.16°C (rough estimate) |
| Density | 0.902 g/mL at 25 °C(lit.) |
| Flash Point | 175 °F |
| Appearance | white to pale grey powder |
| Color | white |
| Form | solid |
| Water Solubility | Slightly soluble |
| Refractive Index | n 20/D 1.4850(lit.) |
| Log P | -0.140 (est) |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29339990 |
| UN Number | 2811 |
| ADR Class | 6.1 |
| Packing Group | III |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 3 |
Documentation
Other Names
Oxitriptan|Griffonia Seed Extract|Griffonia Seed Extract (5-htp)|(2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid|5-Hydroxy-L-tryptophan|5-HTP
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