Fmoc-L-tryptophan

Fmoc-L-tryptophan (CAS 35737-15-6), commonly referenced as Fmoc-Trp-OH, is a protected amino acid building block used in solid-phase peptide synthesis (SPPS).

Where is Fmoc-L-tryptophan used?

• Pharmaceutical peptide production: incorporation into therapeutic sequences where tryptophan residues provide biological activity or structural integrity
• Research and contract synthesis: peptide APIs, libraries and reference standards at discovery and scale
• Biotechnology: peptide-based probes, linkers and conjugates for diagnostic and analytical work
• Academic and industrial chemists rely on it for custom sequence development in early-stage drug candidate screening.

Good to know: The Fmoc group allows sequential, controlled chain assembly under mild deprotection conditions.

Commercial specifications

• Research quantities through to multi-kilogram lots
• Synthesis grade for research; higher-purity specifications for commercial peptide manufacturing