Thioglycolic acid

CAS Number
68-11-1
EC Number
200-677-4
Chemical Formula
C2H4O2S
Molecular Weight
92.12 g/mol
Abbreviation
TGA

Description

Thioglycolic acid (CAS 68-11-1), also known as mercaptoacetic acid and commonly abbreviated as TGA, is an organosulfur acid used across industrial and consumer-facing manufacturing. It functions primarily as a reducing agent, stabilizer, and chemical intermediate in processes requiring controlled thiol reactivity. In personal care, TGA is the active ingredient in permanent wave solutions.

It is used in depilatory creams, where it breaks disulfide bonds in keratin to reshape or dissolve hair. PVC stabilizer production relies on TGA as a key building block for tin and lead mercaptide heat stabilizers. These stabilizers prevent polymer degradation during processing. Leather processing uses TGA to assist in depilation and hide preparation, reducing reliance on sulfide-based alternatives in the tanning industry.

In pharmaceutical manufacturing, it serves as an intermediate in the synthesis of active compounds. It also acts as a reagent in analytical testing for metal ion detection and laboratory research applications. Thioglycolic acid is supplied as a colorless to pale yellow liquid, typically at concentrations of 70%, 80%, and 99%+ for technical and high-purity grades. This ensures versatility for various industrial needs.

Pharmaceutical-grade material is available to USP and BP specifications for regulated manufacturing environments. This high level of purity is essential for sensitive chemical synthesis. Technical-grade material is the standard for polymer stabilizer production and industrial leather processing. We provide consistent quality across all grades to meet specific manufacturing requirements.

Other Names (Synonyms)

thiovanic acid|sulfanylacetic acid|alpha-mercaptoacetic acid|acetyl mercaptan|2-thioglycolic acid|2-mercaptoacetic acid|TGA|mercaptoacetic acid

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -16.5 °C
Boiling Point 120 °C @ Press: 20 Torr
Density 1.3253 g/cm³ @ Temp: 20 °C
Flash Point 126 °C
Appearance Thioglycolic acid is a colorless liquid with a strong unpleasant odor like rotten eggs.
Color clear clear, colorless
Odor strong unpleasant odor
Form Liquid
Water Solubility soluble
Vapor Pressure 0.4 mm Hg ( 25 °C)
Refractive Index n 20/D 1.505(lit.)
pH 1 (H2O, 20℃)
Log P 0.090

Documentation

Safety & Handling Learn More

Danger
GHS05· Corrosive GHS06· Toxic GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H301 Toxic if swallowed
H311 Toxic in contact with skin
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash … thoroughly after handling.

Trade & Regulatory

HS Code 29309070
UN Number 1940
ADR Class 8
Packing Group II
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 1
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