Glyceryl monothioglycolate

CAS Number
30618-84-9
EC Number
250-264-8

What is Glyceryl monothioglycolate?

Glyceryl monothioglycolate (CAS 30618-84-9), also known as glycerol monomercaptoacetate, is a thiol-functional ester used as a reducing agent and surface-modifying ingredient.

Where is Glyceryl monothioglycolate used?

  • Hair care: primary active in acid-wave permanent waving systems, breaking and reforming keratin disulfide bonds to reshape hair structure
  • Textile processing: improves dye uptake and surface uniformity on wool and protein fibers during wet finishing
  • Leather processing: depilatory and fiber-opening agent
  • Paper and specialty substrates: modifies surface chemistry for adhesion or coating receptivity
  • Its free sulfhydryl group enables controlled disulfide bond cleavage in fiber and substrate treatment.

Good to know: Buyers should confirm active assay and stabilizer content before purchase. The compound is sensitive to oxidation during storage, requiring careful handling.

Commercial specifications

  • Cosmetic-grade product manufactured to purity specifications for regulated personal care formulations
  • Technical and cosmetic grades

Other Names (Synonyms)

Mercaptoacetic acid monoester with 1,2,3-propanetriol|Glycerol monomercaptoacetate|Acetic acid, 2-mercapto-, monoester with 1,2,3-propanetriol|0FWE72AF2P|RefChem:663554|Acetic acid, mercapto-, monoester with glycerol|Acetic acid, mercapto-, monoester with 1,2,3-propanetriol|Acetic acid, mercapto-, ester with glycerol

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What are the physical properties of Glyceryl monothioglycolate?

Boiling Point 244°C[at 101 325 Pa]
Density 1.315[at 20℃]
Water Solubility 1000g/L at 20℃
Vapor Pressure 0.001Pa at 25℃
Log P 0.45 at 22℃

How is Glyceryl monothioglycolate classified and handled safely? Learn More

Danger
GHS06· Toxic GHS07· Irritant

Hazard Statements

H301 Toxic if swallowed
H312 Harmful in contact with skin
H317 May cause an allergic skin reaction

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
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