Glyceryl monothioglycolate

CAS Number
30618-84-9
EC Number
250-264-8
Chemical Formula
C5H10O4S
Molecular Weight
166.20 g/mol

Description

Glyceryl monothioglycolate (CAS 30618-84-9), also known as glycerol monomercaptoacetate, is a thiol-functional ester used as a reducing agent and surface-modifying ingredient across personal care and industrial processing applications. Its free sulfhydryl group enables controlled disulfide bond cleavage, making it the active component in permanent wave and hair relaxer formulations as well as fiber and substrate treatment processes.

In professional and retail hair care, it is the primary active in acid-wave permanent waving systems, where it breaks and reforms keratin disulfide bonds to reshape hair structure. Textile processors apply it to wool and protein fibers to improve dye uptake and surface uniformity during wet finishing. In leather processing, it functions as a depilatory and fiber-opening agent.

This chemical supports consistent hide preparation ahead of tanning. Paper and specialty substrate treatments use it to modify surface chemistry for improved adhesion or coating receptivity. Glyceryl monothioglycolate is supplied as a liquid, typically in aqueous solution at defined active concentrations. Technical and cosmetic-grade material is available for various industrial needs.

Cosmetic-grade product is manufactured to purity specifications suitable for inclusion in regulated personal care formulations. Buyers should confirm active assay and stabilizer content before purchase. The compound is sensitive to oxidation during storage, requiring careful handling. Proper documentation ensures the material meets the necessary performance requirements for specialized chemical manufacturing.

Other Names (Synonyms)

Mercaptoacetic acid monoester with 1,2,3-propanetriol|Glycerol monomercaptoacetate|Acetic acid, 2-mercapto-, monoester with 1,2,3-propanetriol|0FWE72AF2P|RefChem:663554|Acetic acid, mercapto-, monoester with glycerol|Acetic acid, mercapto-, monoester with 1,2,3-propanetriol|Acetic acid, mercapto-, ester with glycerol

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Boiling Point 244°C[at 101 325 Pa]
Density 1.315[at 20℃]
Water Solubility 1000g/L at 20℃
Vapor Pressure 0.001Pa at 25℃
Log P 0.45 at 22℃

Safety & Handling (Learn More)

Danger
GHS06· Toxic GHS07· Irritant

Hazard Statements

H301 Toxic if swallowed
H312 Harmful in contact with skin
H317 May cause an allergic skin reaction

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P301+P316 Get emergency medical help immediately.
P302+P352 IF ON SKIN: Wash with plenty of water.
P333+P317 Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.

Documentation

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