Calamine

Calamine (CAS 8011-96-9) is a mineral-based zinc compound used primarily in topical pharmaceutical and personal care formulations. It functions as a mild astringent and skin-soothing agent.

This material is a staple active ingredient in over-the-counter dermatological products. In pharmaceutical manufacturing, it is the primary active in lotions, creams, and sprays formulated to address minor skin irritations.

These products are often sold under formats such as Caladryl and Calamine Plus. Cosmetic formulators incorporate it into mattifying and oil-control products where its absorbent character supports sebum management.

It is frequently used in face powders and primers to control oil. It also appears in calamine-based dusting powders and pediatric skin preparations where a gentle, mineral-derived active is preferred.

Topical spray formats, including Calamine Plus Spray, represent a growing application segment for leave-on dermatological products. This versatility makes it a key component in modern skincare and medicine.

The product is supplied as a fine pink to pale pink powder, with particle size and purity varying by grade. Pharmaceutical-grade material is available to BP and USP specifications.

These quality standards are the most commonly required for regulated topical formulations. Technical-grade material is also available for non-regulated personal care applications where compendial certification is not required.