Simethicone
Description
Simethicone (CAS 8050-81-5) is a mixture of polydimethylsiloxane and silicon dioxide used industrially and pharmaceutically as an antifoaming and defoaming agent. It is recognized across pharmaceutical, food processing, and personal care manufacturing as a reliable foam control ingredient.
In pharmaceutical manufacturing, this compound is incorporated into antiflatulent tablets, suspensions, and chewable formulations to reduce gastrointestinal gas discomfort. Food and beverage processors use it as a process aid to suppress foam during fermentation and cooking.
High-speed filling operations often require foam suppression where excessive foam formation causes production losses. In personal care and cosmetic formulations, it functions as a conditioning and smoothing agent in skin creams, lotions, and hair care products.
Industrial applications include its use in fermentation bioreactors and chemical processing equipment where foam control directly impacts yield and process efficiency. This versatile material ensures that manufacturing processes remain stable and predictable across various sectors.
The product is supplied as a viscous liquid emulsion, typically in concentrations of 30% and 100% active material. USP and NF grades are standard for pharmaceutical and food applications, ensuring high purity for sensitive manufacturing environments.
Food-grade specifications are also available for processing use, meeting the necessary safety requirements for the industry. Bulk supply is available in drums and intermediate bulk containers suited to industrial procurement volumes and large-scale operations.
Physical Properties
| Melting Point | 0 °C (32 °F) |
| Density | 0.980 g/cm³ |
| Flash Point | >101°C |
| Appearance | Viscous, greyish-white, opalescent liquid. |
| Color | Colorless |
| Form | emulsion |
| Vapor Pressure | 5 mm Hg ( 20 °C) |
| Refractive Index | n 20/D 1.406 |
| Log P | 3.404 (est) |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 3910000000 |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 3 |
Documentation
Other Names
Sentry Simethicone|Mylanta Gas Relief|Mylicon Infant's Drops|Sentry Simethicone Emulsion|RefChem:886342|3,3,5,5-tetramethyl-2,4-dioxa-3,5-disilahexane; silanedione|Antifoam A|DC Antifoam A
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