Simethicone

CAS Number
8050-81-5
EC Number
617-098-1
Chemical Formula
Unspecified
Molecular Weight
238.46 g/mol

Description

Simethicone (CAS 8050-81-5) is a mixture of polydimethylsiloxane and silicon dioxide used industrially and pharmaceutically as an antifoaming and defoaming agent. It is recognized across pharmaceutical, food processing, and personal care manufacturing as a reliable foam control ingredient. In pharmaceutical manufacturing, this compound is incorporated into antiflatulent tablets, suspensions, and chewable formulations to reduce gastrointestinal gas discomfort. Food and beverage processors use it as a process aid to suppress foam during fermentation and cooking.

High-speed filling operations often require foam suppression where excessive foam formation causes production losses. In personal care and cosmetic formulations, it functions as a conditioning and smoothing agent in skin creams, lotions, and hair care products. Industrial applications include its use in fermentation bioreactors and chemical processing equipment where foam control directly impacts yield and process efficiency. This versatile material ensures that manufacturing processes remain stable and predictable across various sectors.

The product is supplied as a viscous liquid emulsion, typically in concentrations of 30% and 100% active material. USP and NF grades are standard for pharmaceutical and food applications, ensuring high purity for sensitive manufacturing environments. Food-grade specifications are also available for processing use, meeting the necessary safety requirements for the industry. Bulk supply is available in drums and intermediate bulk containers suited to industrial procurement volumes and large-scale operations.

Other Names (Synonyms)

Sentry Simethicone|Mylanta Gas Relief|Mylicon Infant's Drops|Sentry Simethicone Emulsion|RefChem:886342|3,3,5,5-tetramethyl-2,4-dioxa-3,5-disilahexane; silanedione|Antifoam A|DC Antifoam A

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 0 °C (32 °F)
Density 0.980 g/cm³
Flash Point >101°C
Appearance Viscous, greyish-white, opalescent liquid.
Color Colorless
Form emulsion
Vapor Pressure 5 mm Hg ( 20 °C)
Refractive Index n 20/D 1.406
Log P 3.404 (est)

Documentation

Safety & Handling Learn More

Danger
GHS02· Flammable GHS07· Irritant

Hazard Statements

H225 Highly Flammable liquid and vapor
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H336 May cause drowsiness or dizziness

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.

Trade & Regulatory

HS Code 3910000000
Storage Class 10 - Combustible liquids
WGK (Germany) 3
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