SoleChem

Simethicone

CAS
8050-81-5
EC
617-098-1
Mol. Weight
238.46 g/mol

Description

Simethicone (CAS 8050-81-5) is a mixture of polydimethylsiloxane and silicon dioxide used industrially and pharmaceutically as an antifoaming and defoaming agent. It is recognized across pharmaceutical, food processing, and personal care manufacturing as a reliable foam control ingredient.

In pharmaceutical manufacturing, this compound is incorporated into antiflatulent tablets, suspensions, and chewable formulations to reduce gastrointestinal gas discomfort. Food and beverage processors use it as a process aid to suppress foam during fermentation and cooking.

High-speed filling operations often require foam suppression where excessive foam formation causes production losses. In personal care and cosmetic formulations, it functions as a conditioning and smoothing agent in skin creams, lotions, and hair care products.

Industrial applications include its use in fermentation bioreactors and chemical processing equipment where foam control directly impacts yield and process efficiency. This versatile material ensures that manufacturing processes remain stable and predictable across various sectors.

The product is supplied as a viscous liquid emulsion, typically in concentrations of 30% and 100% active material. USP and NF grades are standard for pharmaceutical and food applications, ensuring high purity for sensitive manufacturing environments.

Food-grade specifications are also available for processing use, meeting the necessary safety requirements for the industry. Bulk supply is available in drums and intermediate bulk containers suited to industrial procurement volumes and large-scale operations.

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Physical Properties

Melting Point 0 °C (32 °F)
Density 0.980 g/cm³
Flash Point >101°C
Appearance Viscous, greyish-white, opalescent liquid.
Color Colorless
Form emulsion
Vapor Pressure 5 mm Hg ( 20 °C)
Refractive Index n 20/D 1.406
Log P 3.404 (est)

Safety & Handling (Learn More)

Danger GHS02 GHS07
Hazard Statements
H225 Highly Flammable liquid and vapor
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H336 May cause drowsiness or dizziness
Precautionary Statements
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P319 Get medical advice/attention if you feel unwell.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P370+P378 Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 3910000000
Storage Class 10 - Combustible liquids
WGK (Germany) 3

Documentation

Other Names

Sentry Simethicone|Mylanta Gas Relief|Mylicon Infant's Drops|Sentry Simethicone Emulsion|RefChem:886342|3,3,5,5-tetramethyl-2,4-dioxa-3,5-disilahexane; silanedione|Antifoam A|DC Antifoam A

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