Disulfiram

CAS Number
97-77-8
EC Number
202-607-8

What is Disulfiram?

Disulfiram (CAS 97-77-8), also known commercially as Tetraethylthiuram Disulfide or TETD, is an organosulfur compound with roles in rubber manufacturing and pharmaceutical production.

Where is Disulfiram used?

  • Rubber and polymer processing: ultra-fast vulcanization accelerator
  • Latex and dry rubber compounds: rapid crosslinking in gloves, seals and industrial goods
  • Pharmaceutical production: API or intermediate for alcohol-aversion therapy formulations
  • Coatings and adhesives: industrial biocide and antifungal agent in preservation systems
  • It also serves in agricultural products and as an antioxidant stabilizer in polymer formulations.

Good to know: Pharmaceutical-grade material is typically subject to stricter documentation. Consistent purity and specification compliance are critical to regulatory approval in medical contexts.

Commercial specifications

  • Bulk quantities for industrial buyers

Other Names (Synonyms)

Tetraethylthiuram Disulphide|Tetraethylthiuram Disulfide|Tetraethylthioperoxydicarbonic Diamide|N,N,N',N'-tetraethylthiuram disulfide|Bis(diethylthiocarbamoyl) disulfide|Antabuse®|Antabuse (tn)

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What are the physical properties of Disulfiram?

Melting Point 71.5 °C
Boiling Point 117 °C @ Press: 17 Torr
Density 1.30 g/cm³
Flash Point 117°C/17mm
Appearance yellow-white crystals or grey powder
Color Light yellow
Odor lt. gray powd., sl. odor
Form Crystals, Crystalline Powder or Granules
Water Solubility 0.02 g/100 mL
Vapor Pressure 0Pa at 25℃
Refractive Index 1.5500 (estimate)
Log P 3.6 at 21℃

How is Disulfiram classified and handled safely? Learn More

Warning
GHS07· Irritant GHS08· Health Hazard GHS09· Environmental Hazard

Hazard Statements

H302 Harmful if swallowed
H303 May be harmful if swallowed
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.

Which trade and regulatory codes apply to Disulfiram?

HS Code 29303000
UN Number 3077
ADR Class 9
Packing Group III
WGK (Germany) 3
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