1,4-butanediol

CAS Number
110-63-4
EC Number
203-786-5
Abbreviation
BDO

What is 1,4-butanediol?

1,4-Butanediol (CAS 110-63-4), commonly abbreviated as BDO, is a four-carbon diol used as a chemical intermediate and solvent in polymer, pharmaceutical, and specialty chemical manufacturing.

Where is 1,4-butanediol used?

  • Engineering plastics, elastic fibers, and polyurethane systems: primary building block
  • PBT and polyurethane: monomer, chain extender and diol component in rigid and flexible formulations
  • Spandex and elastic fibers: reacts with diisocyanates to control segment structure and mechanical performance
  • Pharmaceutical and personal care manufacturing: solvent and carrier for active ingredient delivery in topical and liquid formulations
  • It also serves as a precursor to gamma-butyrolactone and tetrahydrofuran.

Commercial specifications

  • Bulk quantities: ISO tank, drum, and IBC formats
  • Technical and industrial grades most common; high-purity grades for pharmaceutical and specialty chemical applications
  • ≥99% purity standard for most industrial procurement; specifications align with customer-defined purity thresholds

Other Names (Synonyms)

tetramethylene glycol|tetramethylene 1,4-diol|HOCH2CH2CH2CH2OH|HO(CH2)4OH|1,4-tetramethylene glycol|1,4-dihydroxybutane|1,4-butylene glycol|1,4-BD|BDO

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What are the physical properties of 1,4-butanediol?

Melting Point 20.1 °C
Boiling Point 230 °C @ Press: 760 Torr
Density 1.0171 g/cm³ @ Temp: 20 °C
Flash Point 135 °C
Appearance viscous colourless liquid
Color Clear colorless
Odor Odorless
Form Liquid
Water Solubility Miscible
Vapor Pressure <0.1 hPa (20 °C)
Refractive Index n 20/D 1.445(lit.)
pH 7-8 (500g/l, H2O, 20℃)
Log P -0.88 at 25℃

How is 1,4-butanediol classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H336 May cause drowsiness or dizziness

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to 1,4-butanediol?

HS Code 29053980
Storage Class 10 - Combustible liquids
WGK (Germany) 1
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