Pyrithione

CAS Number
1121-31-9
EC Number
214-329-4

What is Pyrithione?

Pyrithione (CAS 1121-31-9), also known as Omadine, is a broad-spectrum antimicrobial active.

Where is Pyrithione used?

  • Personal care: active ingredient in anti-dandruff shampoos and scalp treatments, controlling fungal growth responsible for dandruff
  • Coatings and marine antifouling systems: prevents microbial and algal buildup on surfaces exposed to moisture or immersion
  • Water treatment: controls microbial contamination in industrial process water, cooling towers and recirculating systems
  • Adhesives, sealants and elastomers: in-can or dry-film preservative extending shelf life
  • It targets bacteria, fungi and algae as a biocide and preservative.

Good to know: Purity specifications suited for pharmaceutical and personal care use often meet USP or Ph. Eur. standards. Zinc and sodium salt forms are the most commercially traded derivatives, sourced separately based on formulation compatibility and performance needs.

Commercial specifications

  • Concentration levels vary by application requirement
  • Technical and industrial grades
  • Purity specifications for pharmaceutical and personal care use

Other Names (Synonyms)

Pyridinethiol N-oxide|pyridine-2-thiol-1-oxide|Omadine|2-pyridinethiol, 1-oxide|2-mercaptopyridine-N-oxide|2-mercaptopyridine monoxide|1-oxido-2-pyridinyl hydrosulfide|1-Hydroxy-2-pyridinethione

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What are the physical properties of Pyrithione?

Melting Point 70-73 °C
Boiling Point 350.2±15.0 °C(Predicted)
Density 1.255 (estimate)
Appearance off-white powder
Color Off-white to beige or yellow to yellow-greenish or grayish-green
Form Powder, Crystals, and/or Chunks
Refractive Index 1.5480 (estimate)

How is Pyrithione classified and handled safely? Learn More

Danger
GHS06· Toxic GHS07· Irritant

Hazard Statements

H301 Toxic if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to Pyrithione?

HS Code 29333990
WGK (Germany) 3
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