Vitamin B9 L-5-Methyltetrahydrofolate Glucosamine Salt

Vitamin B9 L-5-Methyltetrahydrofolate Glucosamine Salt (CAS 1181972-37-1) is the glucosamine salt form of (6S)-5-methyltetrahydrofolic acid, a biologically active, reduced folate that is directly utilised at the cellular level without requiring prior metabolic conversion. Supplied as a fine powder with a purity of 98% or above, it is suitable for integration into finished formulations across the supplement, food, pharmaceutical, and personal care sectors. As a bioavailable folate source, L-5-MTHF glucosamine salt is listed in Annex II of Directive 2002/46/EC as a permitted vitamin form in food supplements, supporting its use across EU-regulated product development. Manufacturers working in the nutraceuticals and dietary supplement space can reference the authorised EU health claims under Regulation (EC) No 432/2012, which confirm that Vitamin B9 contributes to normal amino acid synthesis, blood formation, homocysteine metabolism, normal immune system function, and normal maternal tissue growth during pregnancy.

In pharmaceutical and nutraceutical applications, this ingredient is typically formulated into capsules, tablets, and sachets where precise folate delivery is required. Its reduced, active form makes it a technically preferred alternative to synthetic folic acid in premium supplement lines, particularly where formulation briefs call for a metabolically ready folate source. For food and nutrition applications, the ingredient is compatible with functional food and beverage matrices. Its glucosamine salt structure contributes to improved stability under standard processing and storage conditions compared with unstabilised folate forms, a practical consideration for manufacturers working with extended shelf-life products.

In personal care and cosmetic formulations, L-5-MTHF glucosamine salt is utilised as a humectant and stabilising active, supporting moisture retention and antioxidant functionality in topical product development. It is appropriate for inclusion in face serums, creams, and other leave-on formats where ingredient stability and skin compatibility are key formulation criteria. SoleChem supplies this ingredient in food-grade quality, with documentation available to support regulatory submissions and quality management requirements. Typical packaging is offered in 1 kg and 5 kg quantities for development and small-batch production, scaling to 25 kg drums or cartons for commercial-volume procurement. Certificates of Analysis, Safety Data Sheets, and origin documentation are provided as standard.

Prospective buyers requiring technical data sheets, folate equivalence figures per lot, or specification confirmation for their formulation review process are encouraged to contact the SoleChem technical team directly. Samples are available upon request for qualification purposes.