Ubiquinol

CAS Number
992-78-9
EC Number
202-860-4
Chemical Formula
C59H92O4
Molecular Weight
865.36 g/mol

Description

Ubiquinol (CAS 992-78-9) is the reduced, active form of Coenzyme Q10, a lipid-soluble, vitamin-like compound naturally present in human cellular membranes. Distinguished from its oxidised counterpart ubiquinone by its superior bioavailability, ubiquinol is the preferred active form for high-potency nutraceutical and functional food applications. SoleChem supplies pharmaceutical- and food-grade ubiquinol in bulk to manufacturers across Europe. In the nutraceuticals and dietary supplement sector, ubiquinol serves as a primary active ingredient in softgel, capsule, and emulsified liquid formulations. It is commonly positioned as a mitochondrial support and antioxidant ingredient, with established use in finished products dosed typically between 50 mg and 200 mg per serving. Its reduced redox state makes it functionally distinct from standard CoQ10, and it is widely specified in premium supplement lines where bioavailability differentiation is a formulation priority.

For food and functional beverage manufacturers, ubiquinol is suitable for fortification applications where antioxidant stabilisation and nutritional enrichment are required. Water-soluble (CWS) grades, produced via microencapsulation or emulsification technologies, are available for aqueous matrices including beverages, dairy alternatives, and functional foods. These grades facilitate uniform dispersion and label-friendly inclusion at measurable activity levels. In pharmaceutical applications, ubiquinol is incorporated into both oral solid dose and semi-solid formulations. Batches produced to USP or Ph. Eur. reference standards are available on request, with full documentation including certificates of analysis, residual solvent data, and heavy metals testing. Compatibility with GMP-compliant supply chains is supported through appropriate audit documentation and batch traceability.

The personal care and cosmetics industry utilises ubiquinol as a topical antioxidant and skin-conditioning agent. Its capacity to neutralise reactive oxygen species makes it applicable in anti-ageing serums, facial creams, and UV-protective formulations, where it complements existing antioxidant systems. Cosmetic-grade material is supplied with INCI-compliant documentation and meets standard European cosmetics regulatory requirements. Ubiquinol is commercially available in several physical forms to suit diverse manufacturing processes: crystalline powder (white to pale yellow), oil suspension, and microencapsulated CWS powder. Purity grades range from technical through to food-grade and pharmaceutical-grade, and all supplied material is accompanied by specification sheets and safety data documentation.

Standard bulk packaging options include 25 kg fibre drums and cartons for large-volume orders. Smaller lots of 1 kg to 5 kg are available in vacuum-sealed aluminium foil bags, suited to formulation development, scale-up trials, and lower-volume production runs. SoleChem maintains consistent stock availability for European delivery with reliable lead times to support scheduled manufacturing programmes.

Other Names (Synonyms)

ubiquinol-10|CoQ-10|CoQH2-10|Ubiquinol 50|Water Soluble Q10|Dihydrocoenzyme Q10|Reduced Coenzyme Q10

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 48-49°C
Boiling Point 866.9±65.0 °C(Predicted)
Density 0.951±0.06 g/cm3(Predicted)
pka 10.53±0.50(Predicted)
Form A crystalline solid

Documentation

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