Vitamin B9 L-Methylfolate Calcium

Vitamin B9 L-Methylfolate Calcium (CAS 151533-22-1), also known as calcium L-methylfolate or levomefolate calcium, is the calcium salt of the biologically active form of folate. Unlike synthetic folic acid, this compound is the naturally occurring, metabolically ready form of vitamin B9, which makes it a preferred active ingredient across pharmaceutical, nutraceutical, food fortification, and personal care applications where bioavailability and formulation precision are priorities. From a regulatory standpoint, Vitamin B9 L-Methylfolate Calcium is listed in Annex II of Directive 2002/46/EC as an authorised vitamin source for use in food supplements, and recognised under Annex II of Regulation (EC) 1925/2006 for food fortification purposes. Manufacturers working to EU compliance frameworks can therefore incorporate this ingredient with a clear regulatory basis across multiple product categories.

In pharmaceutical and nutraceutical manufacturing, this ingredient is supplied to meet API-grade and compendial specifications including USP and Ph. Eur. standards, supporting tablet, capsule, and powder blend formulations. It carries authorised EU health claims under Regulation (EC) 432/2012, covering contributions to normal amino acid synthesis, blood formation, homocysteine metabolism, immune system function, and maternal tissue growth during pregnancy — all relevant labelling considerations for supplement manufacturers targeting these endpoints. For food and beverage fortification, food-grade Vitamin B9 L-Methylfolate Calcium is suitable for use in functional foods, fortified cereals, dairy alternatives, and infant nutrition products. Its off-white to pale yellow powder appearance and water-solubility profile support integration into both dry blends and liquid formulations, provided appropriate handling conditions are observed.

In personal care and cosmetic applications, the ingredient is used in formulations where folate-related bioactivity and antioxidant stabilisation properties are sought. Product developers working on topical serums, specialised skincare, and hair care lines can specify this ingredient in cosmetic-grade quality to meet their formulation standards. SoleChem supplies Vitamin B9 L-Methylfolate Calcium in crystalline powder form, typically presenting as an off-white to yellow fine powder with controlled moisture and assay specifications. Packaging is available in 1–5 kg lots for development and small-batch production, scaling to 25 kg drums or cartons for commercial manufacturing volumes. Cold-chain or climate-controlled storage recommendations apply in line with product specification sheets.

As a European distributor, SoleChem maintains documentation support including certificates of analysis, safety data sheets, and regulatory dossiers to facilitate supplier qualification and formulation approval workflows. Buyers requiring specific grade confirmation, batch traceability, or third-party testing reports are encouraged to contact our technical sales team directly.