Hexafluoroisopropyl methyl ether

Hexafluoroisopropyl methyl ether (CAS 13171-18-1), also known as HFE-356mmz1, is a fluorinated ether solvent used in specialized pharmaceutical and chemical processing applications. Also referenced as Iso-indoklon in anesthetic research.

Where is Hexafluoroisopropyl methyl ether used?

• Pharmaceutical manufacturing: reaction solvent for fluorine-containing active pharmaceutical ingredient synthesis
• Specialty coatings and fluoropolymer systems: carrier solvent where precise solvency control is required
• Precision manufacturing: cleaning and rinsing solvent
• It has been investigated as an inhalation anesthetic agent.

Good to know: Its fluorinated structure gives low surface tension and selective solvency; chemical inertness prevents unwanted side reactions. Historical research under the Iso-indoklon designation informs modern CNS-active compound development.

Commercial specifications

• High-purity grades for pharmaceutical research and synthesis
• Packaging from small laboratory quantities to bulk supply