Hydroxyethylnitrosourea

Hydroxyethylnitrosourea (CAS 13743-07-2), also referenced as N-(2-hydroxyethyl)-N-nitrosourea, is a nitrosourea compound used primarily in pharmaceutical research and oncology drug development.

Where is Hydroxyethylnitrosourea used?

• Pharmaceutical R&D: reference standard
• Biotechnology laboratories: controlled mutagenesis studies on DNA damage response pathways and repair mechanisms in cell-based assays
• Preclinical screening: benchmarking nitrosourea-type compounds
• Contract research organizations: building block for analog synthesis in structure-activity relationship studies
• It serves as a DNA-alkylating reference agent and research intermediate in cell proliferation and mutagenesis studies.
• It acts as a synthetic intermediate for alkylating chemotherapeutic agents in nitrosourea-class drug programs.

Good to know: Buyers should confirm cold-chain and stability requirements with suppliers prior to procurement. Nitrosourea compounds require controlled storage conditions to maintain integrity.

Commercial specifications

• Research-grade specification
• Purity confirmed by HPLC or NMR
• Solid, small research-scale quantities