Ethacridine lactate

CAS Number
1837-57-6
EC Number
217-408-1

What is Ethacridine lactate?

Ethacridine lactate (CAS 1837-57-6), also marketed as Rivanol and Acrinol, is an antiseptic acridine derivative used in pharmaceutical and healthcare manufacturing.

Where is Ethacridine lactate used?

  • Topical antimicrobial and preservative active
  • Wound care: wound-cleansing solutions, antiseptic creams, gauze dressings targeting bacterial contamination
  • Gynecological preparations: vaginal antiseptic preparations and, in some markets, labor-induction protocols under clinical supervision
  • In aqueous formulations where conventional preservatives are unsuitable, it provides antimicrobial protection.

Good to know: Pharmaceutical-grade material meets BP and Ph. Eur. specifications; technical-grade material is offered for non-medicinal applications.

Commercial specifications

  • Kilogram quantities for formulation development; larger lot sizes for commercial manufacturing

Other Names (Synonyms)

acrinol|Rivanol|6,9-Diamino-2-ethoxyacridine lactate|Metifex|Rimaon|Vucine|Ethodin|Antidiar 200

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What are the physical properties of Ethacridine lactate?

Melting Point 235°C
Boiling Point 478.66°C (rough estimate)
Density 1.2764 (rough estimate)
Appearance Pale-yellow crystals. Slowly soluble in 15 parts water; soluble in 9 parts boiling water; soluble in 110 parts alcohol (22C). Solutions are yellow, fluorescent, and stable to boiling.
Color Pale Yellow to Light Yellow
Form Solid
Refractive Index 1.5855 (estimate)

How is Ethacridine lactate classified and handled safely? Learn More

Warning
GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H411 Toxic to aquatic life with long lasting effects

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
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