Ethacridine lactate
Description
Ethacridine lactate (CAS 1837-57-6), commercially recognized as Rivanol and Acrinol, is an antiseptic acridine derivative used in pharmaceutical and healthcare manufacturing. It functions as a topical antimicrobial and preservative active.
The compound has established use in wound care and gynecological preparations. In topical pharmaceutical formulations, it is incorporated into wound-cleansing solutions, antiseptic creams, and gauze dressings targeting bacterial contamination.
These applications focus on minor wounds and ulcers. Gynecological applications include its use in vaginal antiseptic preparations and, in some markets, as an active in labor-induction protocols under clinical supervision.
As a preservative active in pharmaceutical manufacturing, it provides antimicrobial protection in aqueous formulations where conventional preservatives are unsuitable. This makes it a versatile component for specialized medicine.
Contract manufacturers and compounding pharmacies sourcing for Eastern European, Asian, and Latin American markets represent a significant procurement base. Rivanol-branded products retain a strong market presence in these regions.
Ethacridine lactate is supplied as a yellow crystalline powder. Pharmaceutical-grade material is available to BP and Ph. Eur. specifications, with technical-grade material offered for non-medicinal applications.
Buyers typically source in kilogram quantities for formulation development, with larger lot sizes available for commercial manufacturing runs. This ensures scalability from the laboratory phase to full production cycles.
Physical Properties
| Melting Point | 235°C |
| Boiling Point | 478.66°C (rough estimate) |
| Density | 1.2764 (rough estimate) |
| Appearance | Pale-yellow crystals. Slowly soluble in 15 parts water; soluble in 9 parts boiling water; soluble in 110 parts alcohol (22C). Solutions are yellow, fluorescent, and stable to boiling. |
| Color | Pale Yellow to Light Yellow |
| Form | Solid |
| Refractive Index | 1.5855 (estimate) |
Safety & Handling (Learn More)
Documentation
Other Names
acrinol|Rivanol|6,9-Diamino-2-ethoxyacridine lactate|Metifex|Rimaon|Vucine|Ethodin|Antidiar 200
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