Ethacridine lactate

CAS Number
1837-57-6
EC Number
217-408-1
Chemical Formula
C15H15N3O.C3H6O3
Molecular Weight
343.4 g/mol

Description

Ethacridine lactate (CAS 1837-57-6), commercially recognized as Rivanol and Acrinol, is an antiseptic acridine derivative used in pharmaceutical and healthcare manufacturing. It functions as a topical antimicrobial and preservative active. The compound has established use in wound care and gynecological preparations. In topical pharmaceutical formulations, it is incorporated into wound-cleansing solutions, antiseptic creams, and gauze dressings targeting bacterial contamination.

These applications focus on minor wounds and ulcers. Gynecological applications include its use in vaginal antiseptic preparations and, in some markets, as an active in labor-induction protocols under clinical supervision. As a preservative active in pharmaceutical manufacturing, it provides antimicrobial protection in aqueous formulations where conventional preservatives are unsuitable. This makes it a versatile component for specialized medicine.

Contract manufacturers and compounding pharmacies sourcing for Eastern European, Asian, and Latin American markets represent a significant procurement base. Rivanol-branded products retain a strong market presence in these regions. Ethacridine lactate is supplied as a yellow crystalline powder. Pharmaceutical-grade material is available to BP and Ph. Eur. specifications, with technical-grade material offered for non-medicinal applications.

Buyers typically source in kilogram quantities for formulation development, with larger lot sizes available for commercial manufacturing runs. This ensures scalability from the laboratory phase to full production cycles.

Other Names (Synonyms)

acrinol|Rivanol|6,9-Diamino-2-ethoxyacridine lactate|Metifex|Rimaon|Vucine|Ethodin|Antidiar 200

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 235°C
Boiling Point 478.66°C (rough estimate)
Density 1.2764 (rough estimate)
Appearance Pale-yellow crystals. Slowly soluble in 15 parts water; soluble in 9 parts boiling water; soluble in 110 parts alcohol (22C). Solutions are yellow, fluorescent, and stable to boiling.
Color Pale Yellow to Light Yellow
Form Solid
Refractive Index 1.5855 (estimate)

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H411 Toxic to aquatic life with long lasting effects

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
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