Alpha-GPC (L-Alpha-Glycerylphosphorylcholine)

Alpha-GPC (L-Alpha-Glycerylphosphorylcholine) (CAS 28319-77-9) is a naturally occurring choline-containing phospholipid compound classified within the choline vitamin-like nutrient family. Derived from lecithin through enzymatic or chemical hydrolysis, it serves as a highly bioavailable source of choline and is widely used as a functional ingredient across nutraceutical, pharmaceutical, and personal care formulations. In the nutraceutical and dietary supplement sector, Alpha-GPC is established as a premium choline donor, commonly incorporated into cognitive support, sports nutrition, and healthy ageing formulations. It is typically supplied at an active content of 50% or 99% L-Alpha-Glycerylphosphorylcholine, allowing formulators to select the appropriate concentration for their finished product specifications and dosage targets.

Within pharmaceutical and healthcare applications, Alpha-GPC is recognised under the INN choline alfoscerate and is used as an active pharmaceutical ingredient in several European markets. Manufacturers requiring PhEur- or USP-aligned material can source pharmaceutical-grade material with full documentation support, including certificates of analysis, residual solvent profiles, and heavy metal testing to current compendial standards. In personal care and cosmetic formulations, Alpha-GPC functions as a humectant and skin-conditioning agent. Its hygroscopic properties make it suitable for incorporation into serums, moisturisers, and leave-on treatments where water-binding performance and compatibility with aqueous systems are required. It is also evaluated for mild preservative-supporting activity in certain multi-functional formulations.

SoleChem supplies Alpha-GPC in fine powder form, including both the 50% (typically a hygroscopic powder or granule) and the 99% anhydrous crystalline grade. Cold-water-soluble (CWS) formats are available for applications where rapid dispersibility in aqueous matrices is required. All forms are suitable for encapsulation, tableting, sachet blending, and liquid supplement production. Grade availability covers food/nutraceutical grade and cosmetic grade, with pharmaceutical-grade material available on request with corresponding regulatory documentation. Halal and Kosher certifications are available, supporting manufacturers supplying certified markets. Non-GMO declarations and allergen statements can be provided as standard documentation.

Standard bulk packaging is offered in 25 kg fibre drums with inner polyethylene liner, suitable for industrial-scale production runs. Smaller lots are available in 1 kg and 5 kg heat-sealed foil pouches to support product development, pilot batches, and small-volume manufacturing. All packaging is selected to protect the material from moisture uptake during storage and transit. SoleChem operates as a European distributor with established supply chain infrastructure to support consistent batch availability, lead time reliability, and technical documentation for regulatory submissions across EU and export markets. Samples and technical datasheets are available upon request.