Pyridoxal Hydrochloride

CAS Number
65-22-5
EC Number
200-602-5
Chemical Formula
C8H9NO3.ClH
Molecular Weight
203.62 g/mol

Description

Pyridoxal Hydrochloride (CAS 65-22-5) is the hydrochloride salt form of pyridoxal, one of the naturally occurring vitamers within the Vitamin B6 family. Presented as a white to slightly yellow crystalline powder, it is characterised by a melting point in the range of 171–175 °C (with decomposition) and a molecular formula of C₈H₉NO₃·HCl, giving a molecular weight of approximately 203.62 g/mol. Typical commercial specifications require an assay of ≥ 98.5%, with tightly controlled chloride content in the 17.2–17.7% range. Within the pharmaceutical and nutraceutical sectors, Pyridoxal Hydrochloride serves as an active ingredient in finished-dose formulations and dietary supplement products where a direct aldehyde form of Vitamin B6 is specifically required. Manufacturers should note that this form is not currently listed in Annex II of Directive 2002/46/EC as an authorised source of Vitamin B6 for use in EU food supplements; regulatory due diligence is advised before incorporating it into supplement products targeting European markets.

Vitamin B6 carries a well-established set of authorised EU health claims under Regulation (EC) No 432/2012, including contributions to normal protein and glycogen metabolism, red blood cell formation, normal functioning of the immune system, regulation of hormonal activity, and normal homocysteine metabolism. These claims are relevant to B2B buyers formulating finished products that reference Vitamin B6 activity, subject to applicable compliance requirements. In personal care and cosmetic applications, Pyridoxal Hydrochloride is utilised for its recognised humectant and moisturising properties, as well as its role as a preservation-supporting ingredient in aqueous formulations. It is compatible with a range of cosmetic matrices including serums, leave-on treatments, and scalp-care products where B6 vitamers are specified by the formulation brief.

Quality grades available through SoleChem include material conforming to pharmaceutical compendial standards, suitable for manufacturers requiring documented compliance with USP or Ph. Eur. monograph-aligned specifications. Material is also available in cosmetic-grade and research-grade variants depending on end-use requirements and the purity, bioburden, and endotoxin thresholds applicable to each application. SoleChem supplies Pyridoxal Hydrochloride in standard bulk configurations of 25 kg fibre drums, with smaller packaging options of 1–5 kg available for development-scale or lower-volume requirements. All product is accompanied by a full technical data sheet, certificate of analysis, and safety data sheet aligned with the GHS Warning signal word classification.

Buyers seeking consistent batch-to-batch quality, documented supply chain traceability, and flexible order quantities are invited to contact SoleChem's technical sales team to discuss specifications, lead times, and sample requests.

Other Names (Synonyms)

Pyridoxal HCl|Vitamin B6 hydrochloride|PL HCL|TIMTEC-BB SBB000425|3-HYDROXY-5-HYDROXYMETHYL-2-METHYL-4-PYRIDINAL, HCL|2-METHYL-3-HYDROXY-4-FORMYL-5-HYDROXYMETHYLPYRIDINE HYDROCHLORIDE|3-HYDROXY-5-HYDROXYMETHYL-2-METHYLISONICO-TINALDEHYDE HYDROCHLORIDE

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 165 °C
Water Solubility Soluble in water and ethanol.
Appearance White to off-white crystalline powder
Color White
Form Powder

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
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