Benfotiamine

CAS Number
22457-89-2
EC Number
245-013-4

What is Benfotiamine?

Benfotiamine (CAS 22457-89-2) is a fat-soluble, synthetic derivative of thiamine belonging to the Vitamin B1 family.

Where is Benfotiamine used?

  • Pharmaceutical and nutraceutical: pharma-grade powder meeting IP, BP and USP standards
  • Personal care and cosmetic: antioxidant and stabilising functionality in topical preparations
  • As a Vitamin B1 source it is associated with authorised EU health claims under Regulation (EC) No 432/2012, including contributions to normal energy-yielding metabolism, nervous system, heart and psychological function.

Good to know: Unlike water-soluble thiamine salts, benfotiamine exhibits enhanced lipid permeability. Benfotiamine as a form is not listed in Annex II of Directive 2002/46/EC governing permitted vitamin forms in food supplements within the EU; formulators should carry out their own regulatory due diligence.

Commercial specifications

  • Purity typically at or above 99%
  • Packaging: 25 kg drums and cartons; 1–5 kg lots
  • Moisture-sensitive; refer to specification sheet for shelf life and storage conditions
  • Full COA and MSDS documentation and specification sheets available on request

Other Names (Synonyms)

btmp|berdi|8088c.b.|betivina|biotamin|bietamine|benzoylthiaminemonophosphate

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What are the physical properties of Benfotiamine?

Melting Point 165 °C (decomp)
Boiling Point 745.1±70.0 °C(Predicted)
Density 1.444±0.06 g/cm3(Predicted)
pka 1.84±0.10(Predicted)
Log P -2.814 (est)
Color White to Off-White
Form Solid

How is Benfotiamine classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
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