Vitamin B3 Inositol Hexanicotinate

Vitamin B3 Inositol Hexanicotinate (CAS 6556-11-2) is the esterified form of niacin in which one molecule of inositol is bound to six nicotinic acid moieties.

Where is Vitamin B3 Inositol Hexanicotinate used?

• Nutraceutical and dietary supplement: non-flushing niacin source listed in Annex II of Directive 2002/46/EC as an authorised vitamin B3 source for food supplements in the EU
• Cardiovascular and metabolic health formulations
• Softgels, tablets and hard capsules for circulatory support and cholesterol management
• Pharmaceutical: active ingredient in regulated drug products and combination formulations
• Personal care and cosmetics: skin-conditioning agent and niacin precursor in serums, creams and scalp treatments
• It provides a milder niacin delivery vehicle suited to leave-on products where skin tolerability is a formulation priority.

Good to know: Non-flushing alternative to free nicotinic acid: delivers equivalent vitamin B3 activity without the cutaneous vasodilation response associated with standard niacin supplementation. Niacin contributes to normal energy-yielding metabolism, normal functioning of the nervous system, normal psychological function, normal skin and mucous membranes, and the reduction of tiredness and fatigue under Regulation (EC) No 432/2012.

Commercial specifications

• White to off-white crystalline powder
• Food-grade and pharma-grade options
• USP and Ph. Eur.-aligned specifications where applicable
• 25 kg fibre drums or cartons; 1–5 kg lots for pilot-scale and clinical batch manufacturing