R-Alpha-Lipoic Acid

R-Alpha-Lipoic Acid (CAS 1200-22-2), commonly abbreviated as R-ALA, is the naturally occurring enantiomer of alpha-lipoic acid (thioctic acid) and the biologically active form.

Where is R-Alpha-Lipoic Acid used?

• Nutraceuticals and dietary supplements: bulk active ingredient for encapsulated products, tablets, and stick-pack powders
• Food and nutrition: antioxidant and stabiliser in functional food matrices and fortified beverages
• Processed food: flavouring adjunct and mild acidulant
• Personal care: antioxidant and skin-conditioning agent in serums, creams, and treatment products
• It is compatible with standard emulsion and anhydrous systems.

Good to know: Formulators specify the R-form because it is the stereoisomer found endogenously, distinguishing it from racemic alpha-lipoic acid. Its sensitivity to heat, light, and oxidation requires appropriate handling to preserve activity.

Commercial specifications

• Assay purity, chiral purity (optical rotation), heavy metals, residual solvents, and microbiological limits
• Crystalline and fine-powder forms; particle size and flow characteristics selectable for direct compression, wet granulation, or blending
• Standard and stabilised grades
• 25 kg fibre drums or cartons; 1–5 kg options for development quantities