R-Alpha-Lipoic Acid Sodium Salt

CAS Number
176110-81-9

What is R-Alpha-Lipoic Acid Sodium Salt?

R-Alpha-Lipoic Acid Sodium Salt (CAS 176110-81-9) is the sodium salt form of R-alpha-lipoic acid (R-ALA), a naturally occurring, vitamin-like dithiolane compound recognised for its antioxidant activity in both aqueous and lipid environments.

Where is R-Alpha-Lipoic Acid Sodium Salt used?

  • Pharmaceutical and nutraceutical: active ingredient for oral solid dose forms including capsules and tablets, liquid and softgel applications
  • Food and beverage: functional antioxidant ingredient in fortified foods, meal replacement systems and specialised nutritional products
  • Personal care and cosmetics: antioxidant stabilisation and compatibility with aqueous phases in serums, topical emulsions and anti-ageing preparations
  • The sodium salt dissolves completely in water within minutes with minimal agitation, yielding stable, clear solutions.

Good to know: The primary advantage of this form over racemic alpha-lipoic acid or the free R-acid is its aqueous behaviour. Its stereospecific R-configuration aligns with the naturally biosynthesised enantiomer.

Commercial specifications

  • HPLC purity ≥99%
  • Specific optical rotation +60° to +85°
  • Heavy metals ≤10 ppm
  • Loss on drying ≤3.0%
  • Packaging: 1 kg and 5 kg options, 25 kg drums or cartons

Other Names (Synonyms)

Na-R-ALA|Sodium (R)-lipoate|Sodium (R)-5-(1,2-dithiolan-3-yl)pentanoate|(R)-1,2-Dithiolane-3-pentanoic acid sodium salt

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