R-Alpha-Lipoic Acid Sodium Salt
Description
R-Alpha-Lipoic Acid Sodium Salt (CAS 176110-81-9) is the sodium salt form of R-alpha-lipoic acid (R-ALA), a naturally occurring, vitamin-like dithiolane compound recognised for its antioxidant activity in both aqueous and lipid environments. By converting the free acid to its sodium salt, formulators gain a significantly more water-soluble ingredient, making it a preferred choice wherever clear aqueous systems, rapid dissolution, or improved bioavailability are required. The primary advantage of this form over racemic alpha-lipoic acid or the free R-acid is its aqueous behaviour. Under standard conditions, the sodium salt dissolves completely in water within minutes with minimal agitation, yielding stable, clear solutions — a practical benefit for liquid nutraceutical formats, injectable preparations, and water-based cosmetic systems where the free acid presents solubility or stability challenges.
In the pharmaceutical and nutraceutical sectors, R-Alpha-Lipoic Acid Sodium Salt is supplied as an active ingredient for oral solid dose forms including capsules and tablets, as well as for liquid and softgel applications. Its stereospecific R-configuration aligns with the naturally biosynthesised enantiomer, a consideration increasingly reflected in premium supplement formulations. Material supplied for these end uses is typically characterised by HPLC purity of ≥99%, specific optical rotation within the +60° to +85° range, heavy metals ≤10 ppm, and loss on drying ≤3.0%, consistent with reference standards applied in USP and Ph. Eur.-aligned quality frameworks. For food and beverage manufacturers, food-grade material supports use as a functional antioxidant ingredient in fortified foods, meal replacement systems, and specialised nutritional products. Formulators working in the personal care and cosmetics space utilise the sodium salt in serums, topical emulsions, and anti-ageing preparations where antioxidant stabilisation and compatibility with aqueous phases are formulation priorities.
SoleChem supplies R-Alpha-Lipoic Acid Sodium Salt in fine crystalline powder form. Food-grade and pharma-grade material is available to support qualification across different regulated end-use categories. Packaging is offered in 1 kg and 5 kg options for development quantities and smaller production runs, with 25 kg drums or cartons for bulk commercial supply. Full technical documentation is available on request, including certificates of analysis, specification sheets, safety data sheets, and stability data. SoleChem can support sourcing qualification processes with reference samples and regulatory documentation relevant to EU and international market requirements.
Buyers and procurement teams requiring material for ongoing production, formulation trials, or supplier qualification are invited to contact SoleChem directly for availability, lead times, and technical support.
Other Names (Synonyms)
Na-R-ALA|Sodium (R)-lipoate|Sodium (R)-5-(1,2-dithiolan-3-yl)pentanoate|(R)-1,2-Dithiolane-3-pentanoic acid sodium salt
Key Technical Features
- High Purity Grade standard
- Consistent Batch Quality
- Full Regulatory & REACH Support
- Global Logistics Network enabled