Calcium pidolate

Calcium pidolate (CAS 31377-05-6), also marketed under trade names Efical and Calcidone, is a calcium salt of pyroglutamic acid used as a bioavailable calcium source in nutritional and pharmaceutical applications. Its high solubility and tolerance profile make it a preferred alternative to conventional calcium salts in targeted supplementation formats. In pharmaceutical manufacturing, it is formulated into oral calcium supplements.

These include tablets, sachets, and effervescent formats where superior gastrointestinal tolerability compared to carbonate or citrate forms is a key differentiator for the end user. Functional food and nutraceutical producers incorporate it into fortified beverages, dairy alternatives, and clinical nutrition products requiring soluble, well-absorbed calcium delivery systems.

In animal feed and veterinary nutrition, it serves as a mineral supplement to address calcium deficiencies in livestock and companion animal formulations for better health outcomes. Sports nutrition manufacturers also use it in electrolyte and recovery products targeting bone and muscle support. The material is supplied as a white crystalline powder for easy processing.

It is available in pharmaceutical-grade and food-grade specifications, with material typically conforming to USP or in-house monograph standards depending on the intended application. Packaging ranges from small quantities for R&D use to bulk quantities for commercial production. This ensures flexibility for both laboratory testing and large-scale industrial manufacturing needs.